The primary task of drug development is to screen the targets according to the specificity of human organs. The selection of drug targets through advanced technology can provide precise theoretical support for drug research and development. High-throughput screening (HTS) is the key interface to identify new lead compounds in early stage. A large amount of information can be obtained through HTS, which has been utilized as a method for the discovery of novel targets in various human diseases.
Figure 1. The key interface linking aspects of biological and chemical diversity in HTS. (Michael, et al. 2009)
Figure 2. HTS offers a potential solution for detecting rare biomarkers. (Aniruddha M. et al. 2018)
The HTS advances augur well in regard to the integration of newer technologies that will further accelerate the drug discovery process, although there are still many problems, such as the relationship between the screening results of models in vitro and the overall pharmacological effects. With the advancement of medicine, HTS technology will certainly open up a broader space for the development of novel drugs.