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Human CD19 Stable MC38 Cell Line

Catalog Number CBCL-616
Price Online Inquiry
Unit Quantity 1x106 cells / 1.0 ml


MC38 cell line stable expressing exogenous human CD19 gene


Drug screening and biological assays


CD19 is a type I transmembrane glycoprotein that functions as coreceptor for the B cell antigen receptor complex (BCR) on B cell lymphocytes, and plays a vital role in humoral immune response. CD19 is expressed throughout B cell development from pre-B-cell differentiation with expression persisting until terminal differentiation into plasma cells, and is commonly used as B cell lineage marker; CD19 is also found on most B cell malignancies including chronic lymphocytic leukemias (CLLs), B cell non- Hodgkin's lymphomas (NHLs), and more aggressive B-ALL, which lead to the rapid development of therapeutic antibodies and chimeric antigen receptor therapy.

Product Information

Species Mouse
Host Cell Line MC38
Cell Type Mouse colon cancer cell line
Stability Stable in culture over 10 passages
Growth Properties Adherent
Pharmaceutical Target Immune Molecules
Recommended Medium RPMI1640 + 10% FBS + 5 μg/ml Puromycin
Selection Marker Puromycin
Morphology Monolayer
Seeding Density Thaw entire contents into an appropriate T25 flask.
Subculture Ratio Recommended a ratio of 1:4-1:10.
Storage Method Frozen in liquid nitrogen with 70% medium, 20% FBS and 10% DMSO
Doubling Time
Biosafety Level BSL-1
Shipping Shipping in dry ice
Caution For Research Use Only
For research use only. Not for any other purpose.
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