Kinases belong to the family of phosphotransferases and play critical roles in the process known as phosphorylation
in which a phosphorylated substrate and ADP are produced. Kinases are associated with many complex cellular pathways
including cell metabolism, cell signaling, cell transport etc., which makes them very important to human physiology.
Because of their important cellular functions, kinases have become important drug targets in drug discovery and
development for the treatment of human diseases especially diverse cancers.
Catalog Number: CBCL-22
Species: Mouse
Unit Quantity: 1x106 cells / 1.0 ml
The NRAS proto-oncogene is a member of the Ras gene family, NRAS protein can bind GDP/GTP and possess intrinsic GTPase activity. The NRAS gene provides instructions for making a protein called N-Ras ......
Catalog Number: CBCL-176
Species: Mouse
Unit Quantity: 1x106 cells / 1.0 ml
Mast/Stem Cell Growth Factor Receptor (SCFR; c-Kit) is a member of the subfamily of receptor tyrosine kinases.
Ba/F3, a murine interleukin-3 dependent pro-B cell line is increasingly popular as a ......
Catalog Number: CBCL-212
Species: Mouse
Unit Quantity: 1x106 cells / 1.0 ml
EGFR, the Epidermal growth factor receptor, is a cell-surface receptor tyrosine kinase. EGFR overexpression or overactivity have associated witha number of cancers, including the lung cancer and ......
Catalog Number: CBCL-94
Species: Mouse
Unit Quantity: 1x106 cells / 1.0 ml
EGFR, the Epidermal growth factor receptor, is a cell-surface receptor tyrosine kinase. EGFR overexpression or overactivity have associated witha number of cancers, including the lung cancer and ......
Catalog Number: CBCL-109
Species: Mouse
Unit Quantity: 1x106 cells / 1.0 ml
FMS-like tyrosine kinase 3 (FLT3) is a receptor tyrosine kinase that is expressed almost exclusively in the hematopoietic compartment. Its ligand, FLT3 ligand (FL), induces dimerization and ......
Catalog Number: CBCL-85
Species: Mouse
Unit Quantity: 1x106 cells / 1.0 ml
RET, abbreviated for “rearranged during transfection" is a receptor tyrosine kinase for membranes of the gial cell line-derived neurotropic neurotrophic factor (GDNF) family of extracellular ......
Catalog Number: CBCL-36
Species: Mouse
Unit Quantity: 1x106 cells / 1.0 ml
RET, abbreviated for “rearranged during transfection" is a receptor tyrosine kinase for membranes of the gial cell line-derived neurotropic neurotrophic factor (GDNF) family of extracellular ......
Catalog Number: CBCL-151
Species: Mouse
Unit Quantity: 1x106 cells / 1.0 ml
RET, abbreviated for “rearranged during transfection" is a receptor tyrosine kinase for membranes of the gial cell line-derived neurotropic neurotrophic factor (GDNF) family of extracellular ......
Catalog Number: CBCL-56
Species: Mouse
Unit Quantity: 1x106 cells / 1.0 ml
BRAF is a gene found on chromosome seven that encodes a protein also called BRAF. This protein plays a role in cell growth by sending signals inside the cell promoting, among other functions, cell ......
Catalog Number: CBCL-239
Species: Mouse
Unit Quantity: 1x106 cells / 1.0 ml
Janus kinase 2 (commonly called JAK2) is a non-receptor tyrosine kinase. Mutations in JAK2 have been implicated in polycythemia vera, essential thrombocythemia, and myelofibrosis as well as other ......
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