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Kinases belong to the family of phosphotransferases and play critical roles in the process known as phosphorylation in which a phosphorylated substrate and ADP are produced. Kinases are associated with many complex cellular pathways including cell metabolism, cell signaling, cell transport etc., which makes them very important to human physiology. Because of their important cellular functions, kinases have become important drug targets in drug discovery and development for the treatment of human diseases especially diverse cancers.
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Catalog Number: CBCL-113

Species: Mouse

Unit Quantity: 1x106 cells / 1.0 ml

HER2, also named ERBB2, is a cell-surface receptor tyrosine kinase, ERBB2 overexpression or overactivity have associated with a number of cancers, especially the breast cancer. The identification of ......

Catalog Number: CBCL-198

Species: Mouse

Unit Quantity: 1x106 cells / 1.0 ml

RET, abbreviated for “rearranged during transfection" is a receptor tyrosine kinase for membranes of the gial cell line-derived neurotropic neurotrophic factor (GDNF) family of extracellular ......

Catalog Number: CBCL-78

Species: Mouse

Unit Quantity: 1x106 cells / 1.0 ml

Fibroblast growth factor receptor 2 (FGFR2) also known as CD332, which promotes the proliferation, migration, and invasion of ectopic stromal cells via activation of extracellular-signal-regulated ......

Catalog Number: CBCL-110

Species: Mouse

Unit Quantity: 1x106 cells / 1.0 ml

FMS-like tyrosine kinase 3 (FLT3) is a receptor tyrosine kinase that is expressed almost exclusively in the hematopoietic compartment. Its ligand, FLT3 ligand (FL), induces dimerization and ......

Catalog Number: CBCL-96

Species: Mouse

Unit Quantity: 1x106 cells / 1.0 ml

BCR-ABL is an abnormal protein mostly found in chronic myelogenous leukemia (CML). BCR-ABL and its mutants can promote and maintain the malignant behavior of the cancer cells. The identification of ......

Catalog Number: CBCL-6

Species: Mouse

Unit Quantity: 1x106 cells / 1.0 ml

Platelet-derived growth factor receptor A, abbreviated as PDGFRA or PDGFRa, is a cell-surface receptor tyrosine kinase, and activated by binding of its specific ligand, platelet-derived growth ......

Catalog Number: CBCL-168

Species: Mouse

Unit Quantity: 1x106 cells / 1.0 ml

EML4-ALK, echinoderm microtubule associated protein like 4 - anaplastic lymphoma kinase, is an abnormal protein with transforming activity found in some primary lung malignant tumor. EML4-ALK and its ......

Catalog Number: CBCL-226

Species: Mouse

Unit Quantity: 1x106 cells / 1.0 ml

The KRAS gene provides instructions for making a protein called K-Ras that is part of a signaling pathway known as the RAS/MAPK pathway. The overactivation due to mutation can lead to continuous cell ......

Catalog Number: CBCL-181

Species: Mouse

Unit Quantity: 1x106 cells / 1.0 ml

The KRAS gene provides instructions for making a protein called K-Ras that is part of a signaling pathway known as the RAS/MAPK pathway. The overactivation due to mutation can lead to continuous cell ......

Catalog Number: CBCL-47

Species: Mouse

Unit Quantity: 1x106 cells / 1.0 ml

EGFR, the Epidermal growth factor receptor, is a cell-surface receptor tyrosine kinase. EGFR overexpression or overactivity have associated witha number of cancers, including the lung cancer and ......


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