RM1-PSMA-Luc2-Stable Cell Line
| Catalog Number |
CBCL-0297 |
| Price |
Online Inquiry |
| Unit Quantity |
1 x 10^6 cells / 1.0 ml |
Introduction
This stable RM1 cell line expresses exogenous FOLH (PSMA) gene and luciferase, facilitating studies of PSMA expression and activity.
Application
Drug screening and biological assays
Background
Prostate-specific membrane antigen (PSMA) is a transmembrane glycoprotein that is highly expressed in prostate cancer cells. PSMA is involved in various biological processes, including folate metabolism, cell adhesion, and signal transduction. Due to its high expression in prostate cancer and limited expression in normal tissues, PSMA has become an important target for prostate cancer diagnosis and therapy. PSMA-targeted imaging agents and therapeutic drugs, such as PSMA-PET/CT and PSMA-targeted radioligand therapy, have shown promising results in the management of prostate cancer.
Product Information
| Category |
Luciferase Reporter Cell Lines |
| Cell Line Name |
RM1-PSMA-Luc2-Stable Cell Line |
| Protein Family |
Prostate-specific membrane antigen family |
| Gene |
PSMA |
| Species |
Mouse |
| Host Cell Line |
RM1 |
| Cell Type |
Mouse renal adenocarcinoma |
| Morphology |
Epithelial |
| Growth Properties |
Adherent |
| Selection Marker |
Puromycin |
| Recommended Medium |
RPMI1640+10%FBS+2μg/mL Puromycin |
| Freeze Medium |
70% RPMI1640+20% FBS+10% DMSO |
| Storage Method |
Frozen in liquid nitrogen. |
| Stability |
Validated for at least 10 passages |
| Mycoplasma |
Negative |
| Sterility Testing |
Negative |
| Shipping |
Shipping in dry ice |
| Biosafety Level |
BSL-1 |
| Caution |
For Research Use Only |
For research use only. Not for any other purpose.
