Catalog Number | CBCL-319 |
Price | Online Inquiry |
Unit Quantity | 1x106 cells / 1.0 ml |
HEK293-cAMP-biosensor-22F cell line stable expressing exogenous TAAR1 gene with membrane signal peptide and HA tag
Drug screening and biological assays
Trace-amine associated receptor 1 (TAAR1) is the best-characterized member of the family of TAARs. TAAR1 is widely expressed across the mammalian brain, particularly in limbic and monoaminergic areas, allegedly involved in mood, attention, memory, fear, and addiction. There is evidence to suggest that TAAR1 may be a promising therapeutic target for the treatment of schizophrenia, psychosis in Parkinson's disease, substance use disorders, and the metabolic syndrome and obesity.
Species | Human |
Host Cell Line | KC-2177-HEK293-cAMP-biosensor-22F |
Cell Type | Human embryonic kidney cells |
Stability | Stable in culture over 10 passages |
Growth Properties | Adherent |
Pharmaceutical Target | Immune Molecules |
Recommended Medium | DMEM + 10% FBS + 100 μg/ml Hygromycin B + 9 μg/ml Puromycin |
Selection Marker | Puromycin & Hygromycin B |
Morphology | Epithelial |
Seeding Density | Thaw entire contents into an appropriate T25 flask. |
Subculture Ratio | Recommended a ratio of 1:4-1:5. |
Storage Method | Frozen in liquid nitrogen with 70% medium, 20% FBS and 10% DMSO |
Doubling Time | Approximately 48 hours |
QC | WB |
Biosafety Level | BSL-1 |
Shipping | Shipping in dry ice |
Caution | For Research Use Only |