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TAAR1 Stable HEK293-cAMP-biosensor-membrane Cell Line

Catalog Number CBCL-319
Price Online Inquiry
Unit Quantity 1x106 cells / 1.0 ml

Introduction

HEK293-cAMP-biosensor-22F cell line stable expressing exogenous TAAR1 gene with membrane signal peptide and HA tag

Application

Drug screening and biological assays

Background

Trace-amine associated receptor 1 (TAAR1) is the best-characterized member of the family of TAARs. TAAR1 is widely expressed across the mammalian brain, particularly in limbic and monoaminergic areas, allegedly involved in mood, attention, memory, fear, and addiction. There is evidence to suggest that TAAR1 may be a promising therapeutic target for the treatment of schizophrenia, psychosis in Parkinson's disease, substance use disorders, and the metabolic syndrome and obesity.

Product Information

Category Immune Molecules Cell Lines
Cell Line Name TAAR1 Stable HEK293-cAMP-biosensor-membrane Cell Line
Pharmaceutical Target Immune Molecules
Species Human
Host Cell Line HEK293
Cell Type Human embryonic kidney cells
Morphology Epithelial
Growth Properties Adherent
Selection Marker Puromycin & Hygromycin B
Seeding Density Thaw entire contents into an appropriate T25 flask.
Subculture Ratio Recommended a ratio of 1:4-1:5.
Doubling Time Approximately 48 hours
Recommended Medium DMEM + 10% FBS + 100 μg/ml Hygromycin B + 9 μg/ml Puromycin
Storage Method Frozen in liquid nitrogen with 70% medium, 20% FBS and 10% DMSO
Stability Stable in culture over 10 passages
QC WB
Shipping Shipping in dry ice
Biosafety Level BSL-1
Caution For Research Use Only
For research use only. Not for any other purpose.
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