Catalog Number | CBCL-319 |
Price | Online Inquiry |
Unit Quantity | 1x106 cells / 1.0 ml |
HEK293-cAMP-biosensor-22F cell line stable expressing exogenous TAAR1 gene with membrane signal peptide and HA tag
Drug screening and biological assays
Trace-amine associated receptor 1 (TAAR1) is the best-characterized member of the family of TAARs. TAAR1 is widely expressed across the mammalian brain, particularly in limbic and monoaminergic areas, allegedly involved in mood, attention, memory, fear, and addiction. There is evidence to suggest that TAAR1 may be a promising therapeutic target for the treatment of schizophrenia, psychosis in Parkinson's disease, substance use disorders, and the metabolic syndrome and obesity.
Category | Immune Molecules Cell Lines |
Cell Line Name | TAAR1 Stable HEK293-cAMP-biosensor-membrane Cell Line |
Pharmaceutical Target | Immune Molecules |
Species | Human |
Host Cell Line | HEK293 |
Cell Type | Human embryonic kidney cells |
Morphology | Epithelial |
Growth Properties | Adherent |
Selection Marker | Puromycin & Hygromycin B |
Seeding Density | Thaw entire contents into an appropriate T25 flask. |
Subculture Ratio | Recommended a ratio of 1:4-1:5. |
Doubling Time | Approximately 48 hours |
Recommended Medium | DMEM + 10% FBS + 100 μg/ml Hygromycin B + 9 μg/ml Puromycin |
Storage Method | Frozen in liquid nitrogen with 70% medium, 20% FBS and 10% DMSO |
Stability | Stable in culture over 10 passages |
QC | WB |
Shipping | Shipping in dry ice |
Biosafety Level | BSL-1 |
Caution | For Research Use Only |