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Kinases belong to the family of phosphotransferases and play critical roles in the process known as phosphorylation in which a phosphorylated substrate and ADP are produced. Kinases are associated with many complex cellular pathways including cell metabolism, cell signaling, cell transport etc., which makes them very important to human physiology. Because of their important cellular functions, kinases have become important drug targets in drug discovery and development for the treatment of human diseases especially diverse cancers.
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Catalog Number: CBCL-169

Species: Mouse

Unit Quantity: 1x106 cells / 1.0 ml

FMS-like tyrosine kinase 3 (FLT3) is a receptor tyrosine kinase that is expressed almost exclusively in the hematopoietic compartment. Its ligand, FLT3 ligand (FL), induces dimerization and ......

Catalog Number: CBCL-244

Species: Mouse

Unit Quantity: 1x106 cells / 1.0 ml

c-Met, also called tyrosine-protein kinase Met or hepatocyte growth factor receptor (HGFR), is a protein that in humans is encoded by the MET gene. Abnormal activation of cMet due to overexpression ......

Catalog Number: CBCL-186

Species: Mouse

Unit Quantity: 1x106 cells / 1.0 ml

FGFR4 is a member of the fibroblast growth factor receptor family which play a role in mitogenesis and differentiation. FGFR4 regulates tumor subtype differentiation in luminal breast cancer and ......

Catalog Number: CBCL-166

Species: Mouse

Unit Quantity: 1x106 cells / 1.0 ml

EML4-ALK, echinoderm microtubule associated protein like 4 - anaplastic lymphoma kinase, is an abnormal protein with transforming activity found in some primary lung malignant tumor. EML4-ALK and its ......

Catalog Number: CBCL-254

Species: Human

Unit Quantity: 1x106 cells / 1.0 ml

AKR1B1, also known as AR, is an enzyme that is encoded by the AKR1B1 gene in humans, which belongs to the aldehyde-keto reductase superfamily with a widely expression in human organs. Adapting AKR1B1 ......

Catalog Number: CBCL-15

Species: Mouse

Unit Quantity: 1x106 cells / 1.0 ml

EML4-ALK, echinoderm microtubule associated protein like 4 - anaplastic lymphoma kinase, is an abnormal protein with transforming activity found in some primary lung malignant tumor. EML4-ALK and its ......

Catalog Number: CBCL-73

Species: Mouse

Unit Quantity: 1x106 cells / 1.0 ml

The KRAS gene provides instructions for making a protein called K-Ras that is part of a signaling pathway known as the RAS/MAPK pathway. The overactivation due to mutation can lead to continuous cell ......

Catalog Number: CBCL-10

Species: Mouse

Unit Quantity: 1x106 cells / 1.0 ml

Platelet-derived growth factor receptor A, abbreviated as PDGFRA or PDGFRa, is a cell-surface receptor tyrosine kinase, and activated by binding of its specific ligand, platelet-derived growth ......

Catalog Number: CBCL-243

Species: Mouse

Unit Quantity: 1x106 cells / 1.0 ml

c-Met, also called tyrosine-protein kinase Met or hepatocyte growth factor receptor (HGFR), is a protein that in humans is encoded by the MET gene. Abnormal activation of cMet due to overexpression ......

Catalog Number: CBCL-39

Species: Mouse

Unit Quantity: 1x106 cells / 1.0 ml

EGFR, the Epidermal growth factor receptor, is a cell-surface receptor tyrosine kinase. EGFR overexpression or overactivity have associated witha number of cancers, including the lung cancer and ......


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