Kinases belong to the family of phosphotransferases and play critical roles in the process known as phosphorylation
in which a phosphorylated substrate and ADP are produced. Kinases are associated with many complex cellular pathways
including cell metabolism, cell signaling, cell transport etc., which makes them very important to human physiology.
Because of their important cellular functions, kinases have become important drug targets in drug discovery and
development for the treatment of human diseases especially diverse cancers.
Catalog Number: CBCL-209
Species: Mouse
Unit Quantity: 1x106 cells / 1.0 ml
EGFR, the Epidermal growth factor receptor, is a cell-surface receptor tyrosine kinase. EGFR overexpression or overactivity have associated witha number of cancers, including the lung cancer and ......
Catalog Number: CBCL-241
Species: Mouse
Unit Quantity: 1x106 cells / 1.0 ml
c-Met, also called tyrosine-protein kinase Met or hepatocyte growth factor receptor (HGFR), is a protein that in humans is encoded by the MET gene. Abnormal activation of cMet due to overexpression ......
Catalog Number: CBCL-148
Species: Mouse
Unit Quantity: 1x106 cells / 1.0 ml
IGF1R also named CD221, is a receptor tryrosin kinase activated by a hormone IGF1 and a related hormone IGF2. IGF1R plays an important role in growth, anabolism and body size. The overactivation of ......
Catalog Number: CBCL-12
Species: Mouse
Unit Quantity: 1x106 cells / 1.0 ml
ERBB2, also named HER2, is a cell-surface receptor tyrosine kinase, encoding a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. ERBB2 overexpression or ......
Catalog Number: CBCL-133
Species: Mouse
Unit Quantity: 1x106 cells / 1.0 ml
NTRK2, also named Tropomyosin receptor kinase B (TrkB), is the high affinity catalytic receptor for the neurotrophy and play a major role in neuronal differentiation and survival, was originally ......
Catalog Number: CBCL-118
Species: Mouse
Unit Quantity: 1x106 cells / 1.0 ml
EML4-ALK, echinoderm microtubule associated protein like 4 - anaplastic lymphoma kinase, is an abnormal protein with transforming activity found in some primary lung malignant tumor. EML4-ALK and its ......
Catalog Number: CBCL-87
Species: Mouse
Unit Quantity: 1x106 cells / 1.0 ml
The KRAS gene provides instructions for making a protein called K-Ras that is part of a signaling pathway known as the RAS/MAPK pathway. The overactivation due to mutation can lead to continuous cell ......
Catalog Number: CBCL-74
Species: Mouse
Unit Quantity: 1x106 cells / 1.0 ml
The KRAS gene provides instructions for making a protein called K-Ras that is part of a signaling pathway known as the RAS/MAPK pathway. The overactivation due to mutation can lead to continuous cell ......
Catalog Number: CBCL-167
Species: Mouse
Unit Quantity: 1x106 cells / 1.0 ml
EML4-ALK, echinoderm microtubule associated protein like 4 - anaplastic lymphoma kinase, is an abnormal protein with transforming activity found in some primary lung malignant tumor. EML4-ALK and its ......
Catalog Number: CBCL-242
Species: Mouse
Unit Quantity: 1x106 cells / 1.0 ml
c-Met, also called tyrosine-protein kinase Met or hepatocyte growth factor receptor (HGFR), is a protein that in humans is encoded by the MET gene. Abnormal activation of cMet due to overexpression ......
Related Services:
