Kinases belong to the family of phosphotransferases and play critical roles in the process known as phosphorylation
in which a phosphorylated substrate and ADP are produced. Kinases are associated with many complex cellular pathways
including cell metabolism, cell signaling, cell transport etc., which makes them very important to human physiology.
Because of their important cellular functions, kinases have become important drug targets in drug discovery and
development for the treatment of human diseases especially diverse cancers.
Catalog Number: CBCL-17
Species: Mouse
Unit Quantity: 1x106 cells / 1.0 ml
Kinase insert domain receptor (KDR, a type IV receptor tyrosine kinase) also known as vascular endothelial growth factor receptor 2 (VEGFR-2) is a VEGF receptor. The signalling and trafficking of ......
Catalog Number: CBCL-45
Species: Mouse
Unit Quantity: 1x106 cells / 1.0 ml
EGFR, the Epidermal growth factor receptor, is a cell-surface receptor tyrosine kinase. EGFR overexpression or overactivity have associated witha number of cancers, including the lung cancer and ......
Catalog Number: CBCL-121
Species: Mouse
Unit Quantity: 1x106 cells / 1.0 ml
FMS-like tyrosine kinase 3 (FLT3) is a receptor tyrosine kinase that is expressed almost exclusively in the hematopoietic compartment. Its ligand, FLT3 ligand (FL), induces dimerization and ......
Catalog Number: CBCL-123
Species: Mouse
Unit Quantity: 1x106 cells / 1.0 ml
FMS-like tyrosine kinase 3 (FLT3) is a receptor tyrosine kinase that is expressed almost exclusively in the hematopoietic compartment. Its ligand, FLT3 ligand (FL), induces dimerization and ......
Catalog Number: CBCL-184
Species: Mouse
Unit Quantity: 1x106 cells / 1.0 ml
ERBB2, also named HER2, is a cell-surface receptor tyrosine kinase, encoding a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. ERBB2 overexpression or ......
Catalog Number: CBCL-162
Species: Mouse
Unit Quantity: 1x106 cells / 1.0 ml
FMS-like tyrosine kinase 3 (FLT3) is a receptor tyrosine kinase that is expressed almost exclusively in the hematopoietic compartment. Its ligand, FLT3 ligand (FL), induces dimerization and ......
Catalog Number: CBCL-240
Species: Mouse
Unit Quantity: 1x106 cells / 1.0 ml
RET, abbreviated for “rearranged during transfection" is a receptor tyrosine kinase for membranes of the gial cell line-derived neurotropic neurotrophic factor (GDNF) family of extracellular ......
Catalog Number: CBCL-183
Species: Mouse
Unit Quantity: 1x106 cells / 1.0 ml
The KRAS gene provides instructions for making a protein called K-Ras that is part of a signaling pathway known as the RAS/MAPK pathway. The overactivation due to mutation can lead to continuous cell ......
Catalog Number: CBCL-232
Species: Mouse
Unit Quantity: 1x106 cells / 1.0 ml
The erythropoietin receptor (EpoR) is a protein that in humans is encoded by the EPOR gene. It is a member of the cytokine receptor family. Ba/F3, a murine interleukin-3 dependent pro-B cell line is ......
Catalog Number: CBCL-23
Species: Mouse
Unit Quantity: 1x106 cells / 1.0 ml
The NRAS proto-oncogene is a member of the Ras gene family, NRAS protein can bind GDP/GTP and possess intrinsic GTPase activity. The NRAS gene provides instructions for making a protein called N-Ras ......
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