Kinases belong to the family of phosphotransferases and play critical roles in the process known as phosphorylation
in which a phosphorylated substrate and ADP are produced. Kinases are associated with many complex cellular pathways
including cell metabolism, cell signaling, cell transport etc., which makes them very important to human physiology.
Because of their important cellular functions, kinases have become important drug targets in drug discovery and
development for the treatment of human diseases especially diverse cancers.
Catalog Number: CBCL-147
Species: Mouse
Unit Quantity: 1x106 cells / 1.0 ml
EGFR, the Epidermal growth factor receptor, is a cell-surface receptor tyrosine kinase. EGFR overexpression or overactivity have associated witha number of cancers, including the lung cancer and ......
Catalog Number: CBCL-252
Species: Human
Unit Quantity: 1x106 cells / 1.0 ml
TEK is an angiopoietin receptor that belongs to the protein tyrosine kinase family, which is expressed by endothelial cells and their progenitors, quiescent hematopoietic stem cells (HSCs), and a ......
Catalog Number: CBCL-43
Species: Mouse
Unit Quantity: 1x106 cells / 1.0 ml
EGFR, the Epidermal growth factor receptor, is a cell-surface receptor tyrosine kinase. EGFR overexpression or overactivity have associated witha number of cancers, including the lung cancer and ......
Catalog Number: CBCL-14
Species: Mouse
Unit Quantity: 1x106 cells / 1.0 ml
ERBB2, also named HER2, is a cell-surface receptor tyrosine kinase, encoding a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. ERBB2 overexpression or ......
Catalog Number: CBCL-172
Species: Mouse
Unit Quantity: 1x106 cells / 1.0 ml
FGFR4 is a member of the fibroblast growth factor receptor family which play a role in mitogenesis and differentiation. FGFR4 regulates tumor subtype differentiation in luminal breast cancer and ......
Catalog Number: CBCL-3
Species: Mouse
Unit Quantity: 1x106 cells / 1.0 ml
LTK is a member of the anaplastic lymphoma kinase (ALK)/LTK subfamily within the insulin receptor superfamily of RTKs. Although LTK can activate the RAS/MAPK and PI3K/AKT pathways and is expressed in ......
Catalog Number: CBCL-95
Species: Mouse
Unit Quantity: 1x106 cells / 1.0 ml
BCR-ABL is an abnormal protein mostly found in chronic myelogenous leukemia (CML). BCR-ABL and its mutants can promote and maintain the malignant behavior of the cancer cells. The identification of ......
Catalog Number: CBCL-5
Species: Mouse
Unit Quantity: 1x106 cells / 1.0 ml
The FGFR3 gene provides instructions for making a protein called fibroblast growth factor receptor 3. Gain of function mutations in FGFR3 inhibits chondrocyte proliferation and underlies ......
Catalog Number: CBCL-230
Species: Mouse
Unit Quantity: 1x106 cells / 1.0 ml
The KRAS gene provides instructions for making a protein called K-Ras that is part of a signaling pathway known as the RAS/MAPK pathway. The overactivation due to mutation can lead to continuous cell ......
Catalog Number: CBCL-48
Species: Mouse
Unit Quantity: 1x106 cells / 1.0 ml
EGFR, the Epidermal growth factor receptor, is a cell-surface receptor tyrosine kinase. EGFR overexpression or overactivity have associated witha number of cancers, including the lung cancer and ......
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