Kinases belong to the family of phosphotransferases and play critical roles in the process known as phosphorylation
in which a phosphorylated substrate and ADP are produced. Kinases are associated with many complex cellular pathways
including cell metabolism, cell signaling, cell transport etc., which makes them very important to human physiology.
Because of their important cellular functions, kinases have become important drug targets in drug discovery and
development for the treatment of human diseases especially diverse cancers.
Catalog Number: CBCL-225
Species: Mouse
Unit Quantity: 1x106 cells / 1.0 ml
EGFR, the Epidermal growth factor receptor, is a cell-surface receptor tyrosine kinase. EGFR overexpression or overactivity have associated witha number of cancers, including the lung cancer and ......
Catalog Number: CBCL-158
Species: Mouse
Unit Quantity: 1x106 cells / 1.0 ml
FMS-like tyrosine kinase 3 (FLT3) is a receptor tyrosine kinase that is expressed almost exclusively in the hematopoietic compartment. Its ligand, FLT3 ligand (FL), induces dimerization and ......
Catalog Number: CBCL-52
Species: Mouse
Unit Quantity: 1x106 cells / 1.0 ml
c-Met, also called tyrosine-protein kinase Met or hepatocyte growth factor receptor (HGFR), is a protein that in humans is encoded by the MET gene. Abnormal activation of cMet due to overexpression ......
Catalog Number: CBCL-21
Species: Mouse
Unit Quantity: 1x106 cells / 1.0 ml
EGFR, the Epidermal growth factor receptor, is a cell-surface receptor tyrosine kinase. EGFR overexpression or overactivity have associated witha number of cancers, including the lung cancer and ......
Catalog Number: CBCL-38
Species: Mouse
Unit Quantity: 1x106 cells / 1.0 ml
Bruton's tyrosine kinase (abbreviated BTK) is a tyrosine kinase, which plays a key role in B cell development and maturation.
Ba/F3, a murine interleukin-3 dependent pro-B cell line is increasingly ......
Catalog Number: CBCL-190
Species: Mouse
Unit Quantity: 1x106 cells / 1.0 ml
BRAF is a gene found on chromosome seven that encodes a protein also called BRAF. This protein plays a role in cell growth by sending signals inside the cell promoting, among other functions, cell ......
Catalog Number: CBCL-42
Species: Mouse
Unit Quantity: 1x106 cells / 1.0 ml
The KRAS gene provides instructions for making a protein called K-Ras that is part of a signaling pathway known as the RAS/MAPK pathway. The overactivation due to mutation can lead to continuous cell ......
Catalog Number: CBCL-124
Species: Mouse
Unit Quantity: 1x106 cells / 1.0 ml
FMS-like tyrosine kinase 3 (FLT3) is a receptor tyrosine kinase that is expressed almost exclusively in the hematopoietic compartment. Its ligand, FLT3 ligand (FL), induces dimerization and ......
Catalog Number: CBCL-115
Species: Mouse
Unit Quantity: 1x106 cells / 1.0 ml
Mast/Stem Cell Growth Factor Receptor (SCFR; c-Kit) is a member of the subfamily of receptor tyrosine kinases.
Ba/F3, a murine interleukin-3 dependent pro-B cell line is increasingly popular as a ......
Catalog Number: CBCL-197
Species: Mouse
Unit Quantity: 1x106 cells / 1.0 ml
EGFR, the Epidermal growth factor receptor, is a cell-surface receptor tyrosine kinase. EGFR overexpression or overactivity have associated witha number of cancers, including the lung cancer and ......
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