| Catalog Number | CBCL-0146 |
| Price | Online Inquiry |
| Unit Quantity | 1 x 10^6 cells / 1.0 ml |
Recombinant 1321N1 cells have been developed to stably overexpress human pyrimidinergic receptor P2Y6 (P2Y6) on their surface. These cells contain high levels of the G protein Gαq, which is crucial for coupling with the receptor in downstream signaling pathways.
Drug screening and biological assays
P2Y6 is a receptor for extracellular UDP. It is involved in immune responses, inflammation, and other physiological processes.
| Category | GPCR Cell Lines |
| Cell Line Name | 1321N1-P2Y6-Stable Cell Line |
| Protein Family | P5Y receptor |
| Gene | P2Y6 |
| NCBI Gene ID | 5031 |
| Species | Human |
| Host Cell Line | 1321N1 |
| Cell Type | Human astrocytoma cell line |
| Morphology | Fibroblast-like |
| Growth Properties | Adherent |
| Recommended Medium | DMEM, 10% FBS, 100 μg/ml Geneticin |
| Freeze Medium | 45% culture medium + 45% FBS + 10% DMSO |
| Storage Method | Frozen in liquid nitrogen. |
| Stability | Validated for at least 10 passages |
| Mycoplasma | Negative |
| Sterility Testing | Negative |
| Shipping | Shipping in dry ice |
| Biosafety Level | BSL-1 |
| Caution | For Research Use Only |