Ba/F3-EGFR-Del19/T790M/C797S-Luc2-Stable Cell Line
| Catalog Number |
CBCL-0359 |
| Price |
Online Inquiry |
| Unit Quantity |
1 x 10^6 cells / 1.0 ml |
Introduction
This stable Ba/F3 cell line expresses exogenous EGFR isoform a with exon19 E746-A750 deletion, T790M, and C797S triple mutations, along with luciferase, enabling studies of EGFR signaling and activity.
Application
Drug screening and biological assays
Background
EGFR Del19/T790M/C797S refers to a triple mutation form of the EGFR gene, including exon 19 deletion and point mutations T790M and C797S, which is associated with resistance to certain EGFR-targeted therapies in lung cancer.
Product Information
| Category |
Fluorescence Labeled Cell Lines |
| Cell Line Name |
Ba/F3-EGFR-Del19/T790M/C797S-Luc2-Stable Cell Line |
| Protein Family |
Epidermal growth factor receptor family |
| Gene |
EGFR Del19/T790M/C797S |
| Species |
Human |
| Host Cell Line |
Ba/F3 |
| Cell Type |
Murine pro-B cell line |
| Morphology |
Lymphoblastoid |
| Growth Properties |
Suspension |
| Selection Marker |
Puromycin, Hygromycin B |
| Recommended Medium |
RPMI1640+10%FBS+1mg/mL Hygromycin B |
| Freeze Medium |
70% RPMI1640+20% FBS+10% DMSO |
| Storage Method |
Frozen in liquid nitrogen. |
| Stability |
Validated for at least 10 passages |
| Mycoplasma |
Negative |
| Sterility Testing |
Negative |
| Shipping |
Shipping in dry ice |
| Biosafety Level |
BSL-1 |
| Caution |
For Research Use Only |
For research use only. Not for any other purpose.
