Ba/F3-EGFR-Del19/T790M/C797S-Luc2-Stable Cell Line
| Catalog Number | CBCL-0359 |
| Price | Online Inquiry |
| Unit Quantity | 1 x 10^6 cells / 1.0 ml |
Introduction
This stable Ba/F3 cell line expresses exogenous EGFR isoform a with exon19 E746-A750 deletion, T790M, and C797S triple mutations, along with luciferase, enabling studies of EGFR signaling and activity.
Application
Drug screening and biological assays
Background
EGFR Del19/T790M/C797S refers to a triple mutation form of the EGFR gene, including exon 19 deletion and point mutations T790M and C797S, which is associated with resistance to certain EGFR-targeted therapies in lung cancer.
Product Information
| Category | Fluorescence Labeled Cell Lines |
| Cell Line Name | Ba/F3-EGFR-Del19/T790M/C797S-Luc2-Stable Cell Line |
| Protein Family | Epidermal growth factor receptor family |
| Gene | EGFR Del19/T790M/C797S |
| Species | Human |
| Host Cell Line | Ba/F3 |
| Cell Type | Murine pro-B cell line |
| Morphology | Lymphoblastoid |
| Growth Properties | Suspension |
| Storage Method | Frozen in liquid nitrogen. |
| Stability | Validated for at least 10 passages |
| Mycoplasma | Negative |
| Sterility Testing | Negative |
| Shipping | Shipping in dry ice |
| Caution | For Research Use Only |
For research use only. Not for any other purpose.