Ba/F3-ERBB2-A775-G776insYVMA-Luc2-Stable Cell Line
| Catalog Number |
CBCL-0307 |
| Price |
Online Inquiry |
| Unit Quantity |
1 x 10^6 cells / 1.0 ml |
Introduction
This stable Ba/F3 cell line expresses exogenous ERBB2 with an A775-G776 YVMA insertion and luciferase, enabling studies of ERBB2 signaling and activity.
Application
Drug screening and biological assays
Background
ERBB2 A775-G776insYVMA is an insertion mutation in the ERBB2 (HER2) gene, which is associated with increased activity of the HER2 protein and is found in certain breast and other cancers.
Product Information
| Category |
Luciferase Reporter Cell Lines |
| Cell Line Name |
Ba/F3-ERBB2-A775-G776insYVMA-Luc2-Stable Cell Line |
| Protein Family |
Erb-B2 receptor tyrosine kinase 2 family |
| Gene |
ERBB2 A775-G776insYVMA |
| Species |
Human |
| Host Cell Line |
Ba/F3 |
| Cell Type |
Murine pro-B cell line |
| Morphology |
Lymphoblastoid |
| Growth Properties |
Suspension |
| Selection Marker |
Puromycin |
| Recommended Medium |
RPMI1640+10%FBS |
| Freeze Medium |
70% RPMI1640+20% FBS+10% DMSO |
| Storage Method |
Frozen in liquid nitrogen. |
| Stability |
Validated for at least 10 passages |
| Mycoplasma |
Negative |
| Sterility Testing |
Negative |
| Shipping |
Shipping in dry ice |
| Biosafety Level |
BSL-1 |
| Caution |
For Research Use Only |
For research use only. Not for any other purpose.
