Ba/F3-IL-5 Responsive Luciferase Reporter-Stable Cell Line
| Catalog Number |
CBCL-0733 |
| Price |
Online Inquiry |
| Unit Quantity |
2 x 10^6 cells / 1.0 ml |
Introduction
The Ba/F3-IL-5 Responsive Luciferase Reporter-Stable Cell Line is a murine Ba/F3 cell line that expresses human IL-5RA and human CSF2RB. This cell line responds to IL-5, and IL-5-induced luciferase activity can be inhibited by anti-IL-5 or anti-IL-5R neutralizing antibodies.
Application
Drug screening and biological assays
Background
IL - 5 (Interleukin - 5) is a cytokine that is primarily produced by Th2 cells and eosinophils. It acts on eosinophils to promote their growth, differentiation, and activation, and is involved in allergic responses, asthma, and the defense against parasitic infections.
Product Information
| Category |
Cell Signaling Cell Lines |
| Cell Line Name |
Ba/F3-IL-5 Responsive Luciferase Reporter-Stable Cell Line |
| Protein Family |
Interleukin receptor family |
| Gene |
IL-5 |
| NCBI Gene ID |
3567 |
| Species |
Human |
| Host Cell Line |
Ba/F3 |
| Cell Type |
Murine pro-B cell line |
| Morphology |
Lymphoblastoid |
| Growth Properties |
Suspension |
| Recommended Medium |
RPMI-1640 medium + 10% FBS |
| Freeze Medium |
90% FBS + 10% DMSO |
| Storage Method |
Liquid Nitrogen |
| Stability |
Validated for at least 10 passages |
| Mycoplasma |
Negative |
| Sterility Testing |
Negative |
| Shipping |
Shipping in dry ice |
| Biosafety Level |
BSL-1 |
| Caution |
For Research Use Only |
For research use only. Not for any other purpose.
