Catalog Number | CBCL-584 |
Price | Online Inquiry |
Unit Quantity | 1x106 cells / 1.0 ml |
Stable RS4;11 expressing exogenous BCL2 gene bearing F104L amino acid mutation.
Drug screening and biological assays
Bcl-2 (B-cell lymphoma 2), as it is the second member of a range of proteins initially described in chromosomal translocations involving chromosomes 14 and 18 in follicular lymphomas. Bcl-2-family proteins regulate all major types of cell death, including apoptosis, necrosis and autophagy, thus operating as nodal points at the convergence of multiple pathways with broad relevance to oncology.
Category | Immune Molecules Cell Lines |
Cell Line Name | BCL2-F104L Stable RS4;11 Cell Line |
Pharmaceutical Target | Immune Molecules |
Species | Human |
Host Cell Line | RS4;11 |
Cell Type | Acute lymphoblastic leukemia, Lymphoblast |
Morphology | lymphoblastoid |
Growth Properties | Suspension |
Selection Marker | Puromycin |
Seeding Density | Thaw entire contents into an appropriate T25 flask. |
Subculture Ratio | Recommended a ratio of 1:3. |
Recommended Medium | RPMI1640 + 10% FBS + 1 μg/ml Puromycin |
Storage Method | Frozen in liquid nitrogen with 70% medium, 20% FBS and 10% DMSO |
Stability | Stable in culture over 10 passages |
QC | WB |
Shipping | Shipping in dry ice |
Biosafety Level | BSL-1 |
Caution | For Research Use Only |