BCL2-G101V Stable RS4;11 Cell Line
| Catalog Number |
CBCL-582 |
| Price |
Online Inquiry |
| Unit Quantity |
1x106 cells / 1.0 ml |
Introduction
Stable RS4;11 expressing exogenous BCL2 gene bearing G101V amino acid mutation.
Application
Drug screening and biological assays
Background
Bcl-2 (B-cell lymphoma 2), as it is the second member of a range of proteins initially described in chromosomal translocations involving chromosomes 14 and 18 in follicular lymphomas. Bcl-2-family proteins regulate all major types of cell death, including apoptosis, necrosis and autophagy, thus operating as nodal points at the convergence of multiple pathways with broad relevance to oncology.
Product Information
| Species |
Human |
| Host Cell Line |
RS4;11 |
| Cell Type |
Acute lymphoblastic leukemia, Lymphoblast |
| Stability |
Stable in culture over 10 passages |
| Growth Properties |
Suspension |
| Pharmaceutical Target |
Immune Molecules |
| Recommended Medium |
RPMI1640 + 10% FBS + 1 μg/ml Puromycin |
| Selection Marker |
Puromycin |
| Morphology |
Lymphoblast |
| Seeding Density |
Thaw entire contents into an appropriate T25 flask. |
| Subculture Ratio |
Recommended a ratio of 1:3. |
| Storage Method |
Frozen in liquid nitrogen with 70% medium, 20% FBS and 10% DMSO |
| Doubling Time |
|
| QC |
WB |
| Biosafety Level |
BSL-1 |
| Shipping |
Shipping in dry ice |
| Caution |
For Research Use Only |
For research use only. Not for any other purpose.
