Contact Us

USA

Tel:
Fax:
Email:
Europe
Tel:
Email:

BCR-FGFR1 Stable Ba/F3 Cell Line

Catalog Number CBCL-90
Price Online Inquiry
Unit Quantity 1x106 cells / 1.0 ml

Introduction

Stable Ba/F3 clone expressing exogenous BCR-FGFR1 fusion genes.

Application

Drug screening and biological assays

Background

FGFR1, also named as CD331, is a receptor tyrosine kinase belonging to the fibroblast growth factor recepter family. This gene is involved in a type of blood cancer called 8p11 myeloproliferative syndrome. This condition is characterized by an increased number of white blood cells and the development of lymphoma. Ba/F3, a murine interleukin-3 dependent pro-B cell line is increasingly popular as a model system for assessing both the potency and downstream signaling of kinase oncogenes, and the ability of small-molecule kinase inhibitors to block kinase activity.

Product Information

Category Kinase Cell Lines
Cell Line Name BCR-FGFR1 Stable Ba/F3 Cell Line
Pharmaceutical Target Kinases
Species Mouse
Host Cell Line Ba/F3
Cell Type Pro-B cells
Morphology Mostly round
Growth Properties Suspension
Selection Marker Puromycin
Seeding Density Thaw entire contents into an appropriate T25 flask.
Subculture Ratio Recommended a ratio of 1:10.
Doubling Time Approximately 20 hours
Recommended Medium RPMI 1640 + 10% FBS
Storage Method Frozen in liquid nitrogen with 70% medium, 20% FBS and 10% DMSO
Stability Stable in culture over 10 passages
QC WB
Shipping Shipping in dry ice
Biosafety Level BSL-1
Caution For Research Use Only
For research use only. Not for any other purpose.
Copyright © 2025 Creative Bioarray. All rights reserved.