| Catalog Number | CBCL-0710 |
| Price | Online Inquiry |
| Unit Quantity | 2 x 10^6 cells / 1.0 ml |
The CGRPR/CRE Luciferase Reporter HEK293 Cell Line is a recombinant HEK293 cell line stably expressing full-length human Calcitonin receptor-like receptor (CALCRL/CRLR/CLR) and containing a firefly luciferase gene under the control of multimerized cAMP response element (CRE).
Drug screening and biological assays
CALCRL (Calcitonin Receptor Like Receptor) forms a receptor complex with receptor activity - modifying proteins (RAMP) to bind calcitonin gene - related peptide (CGRP) and adrenomedullin. It is involved in various physiological processes such as vasodilation, neurotransmission, and pain perception.
| Category | Cell Signaling Cell Lines |
| Cell Line Name | CGRPR/CRE Luciferase Reporter HEK293 Cell Line |
| Protein Family | Calcitonin gene-related peptide receptor family |
| Gene | CGRPR |
| Species | Human |
| Host Cell Line | HEK293 |
| Cell Type | Human embryonic kidney cells |
| Morphology | Epithelial |
| Growth Properties | Adherent |
| Recommended Medium | DMEM medium + 10% FBS |
| Freeze Medium | 90% FBS + 10% DMSO |
| Storage Method | Liquid Nitrogen |
| Stability | Validated for at least 10 passages |
| Mycoplasma | Negative |
| Sterility Testing | Negative |
| Shipping | Shipping in dry ice |
| Biosafety Level | BSL-1 |
| Caution | For Research Use Only |