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CGRPR/CRE Luciferase Reporter HEK293 Cell Line

Catalog Number CBCL-0710
Price Online Inquiry
Unit Quantity 2 x 10^6 cells / 1.0 ml

Introduction

The CGRPR/CRE Luciferase Reporter HEK293 Cell Line is a recombinant HEK293 cell line stably expressing full-length human Calcitonin receptor-like receptor (CALCRL/CRLR/CLR) and containing a firefly luciferase gene under the control of multimerized cAMP response element (CRE).

Application

Drug screening and biological assays

Background

CALCRL (Calcitonin Receptor Like Receptor) forms a receptor complex with receptor activity - modifying proteins (RAMP) to bind calcitonin gene - related peptide (CGRP) and adrenomedullin. It is involved in various physiological processes such as vasodilation, neurotransmission, and pain perception.

Product Information

Category Cell Signaling Cell Lines
Cell Line Name CGRPR/CRE Luciferase Reporter HEK293 Cell Line
Protein Family Calcitonin gene-related peptide receptor family
Gene CGRPR
Species Human
Host Cell Line HEK293
Cell Type Human embryonic kidney cells
Morphology Epithelial
Growth Properties Adherent
Recommended Medium DMEM medium + 10% FBS
Freeze Medium 90% FBS + 10% DMSO
Storage Method Liquid Nitrogen
Stability Validated for at least 10 passages
Mycoplasma Negative
Sterility Testing Negative
Shipping Shipping in dry ice
Biosafety Level BSL-1
Caution For Research Use Only
For research use only. Not for any other purpose.
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