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CGRPR/CRE Luciferase Reporter HEK293 Cell Line

Catalog Number CBCL-0710
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Unit Quantity 2 x 10^6 cells / 1.0 ml

Introduction

The CGRPR/CRE Luciferase Reporter HEK293 Cell Line is a recombinant HEK293 cell line stably expressing full-length human Calcitonin receptor-like receptor (CALCRL/CRLR/CLR) and containing a firefly luciferase gene under the control of multimerized cAMP response element (CRE).

Application

Drug screening and biological assays

Background

CALCRL (Calcitonin Receptor Like Receptor) forms a receptor complex with receptor activity - modifying proteins (RAMP) to bind calcitonin gene - related peptide (CGRP) and adrenomedullin. It is involved in various physiological processes such as vasodilation, neurotransmission, and pain perception.

Product Information

Category Cell Signaling Cell Lines
Cell Line Name CGRPR/CRE Luciferase Reporter HEK293 Cell Line
Protein Family Calcitonin gene-related peptide receptor family
Gene CGRPR
Species Human
Host Cell Line HEK293
Cell Type Human embryonic kidney cells
Morphology Epithelial
Growth Properties Adherent
Storage Method Liquid Nitrogen
Stability Validated for at least 10 passages
Mycoplasma Negative
Sterility Testing Negative
Shipping Shipping in dry ice
Caution For Research Use Only
For research use only. Not for any other purpose.