CHO-Human BTLA-Stable Cell Line
| Catalog Number | CBCL-0573 |
| Price | Online Inquiry |
| Unit Quantity | 5 x 10^6 cells / 1.0 ml |
Introduction
The CHO-Human BTLA-Stable Cell Line is engineered to express the receptor full-length human BTLA (Uniprot: Q7Z6A9-1), used to mimic cancer target cells. When co-cultured with human HVEM Reporter Cell, the BTLA/HVEM interaction drives NF-kB-mediated luminescence. Blocking the BTLA/HVEM interaction by either anti-BTLA or anti-HVEM antibodies results in a decrease in luminescence.
Application
Useful for cell-based BTLA binding assay
Background
BTLA (B and T Lymphocyte Attenuator) is an inhibitory receptor expressed on T cells, B cells, and NK cells. It binds to HVEM (TNFRSF14) and delivers inhibitory signals that suppress lymphocyte activation, promoting immune tolerance.
Product Information
| Category | Immune Checkpoint Cell Lines |
| Cell Line Name | CHO-Human BTLA-Stable Cell Line |
| Protein Family | B and T lymphocyte attenuator family |
| Gene | BTLA |
| Species | Hamster |
| Host Cell Line | CHO |
| Cell Type | Chinese hamster ovary cell line |
| Morphology | Epithelial |
| Growth Properties | Adherent |
| Storage Method | Frozen in liquid nitrogen. |
| Stability | Validated for at least 10 passages |
| Mycoplasma | Negative |
| Sterility Testing | Negative |
| Shipping | Shipping in dry ice |
| Caution | For Research Use Only |
For research use only. Not for any other purpose.