CHO-Human CD16a (158F)-Stable Cell Line
| Catalog Number |
CBCL-0001 |
| Price |
Online Inquiry |
| Unit Quantity |
5 x 10^6 cells / 1.0 ml |
Introduction
A CHO cell line that stably expresses the full - length human CD16a (158F) has been developed.
Application
Useful for cell-based CD16a (158F) binding assay.
Background
The FCGR3A gene encodes a low-affinity receptor for the Fc region of immunoglobulin G (IgG). It is expressed on the surface of natural killer (NK) cells, macrophages, and some T cells. This receptor plays a crucial role in antibody-dependent cellular cytotoxicity (ADCC), where it binds to the Fc portion of antibodies attached to target cells, leading to the activation of immune cells and the destruction of the target cells. It is also involved in the regulation of immune responses and inflammation.
Product Information
| Category |
Fc Receptor Cell Lines |
| Cell Line Name |
CHO-Human CD16a (158F)-Stable Cell Line |
| Protein Family |
Fc gamma receptor |
| Gene |
CD16a/FCGR3A |
| NCBI Gene ID |
2214 |
| Species |
Hamster |
| Host Cell Line |
CHO |
| Cell Type |
Chinese hamster ovary cell line |
| Morphology |
Epithelial |
| Growth Properties |
Adherent |
| Selection Marker |
Hygromycin B (20 μg/mL) |
| Recommended Medium |
F-12K + 10% FBS |
| Freeze Medium |
Serum-free cell cryopreservation medium |
| Storage Method |
Frozen in liquid nitrogen. |
| Stability |
Validated for at least 10 passages |
| Mycoplasma |
Negative |
| Sterility Testing |
Negative |
| Shipping |
Shipping in dry ice |
| Biosafety Level |
BSL-1 |
| Caution |
For Research Use Only |
For research use only. Not for any other purpose.
