CHO-Human CD32a (131H)-Medium Expression-Stable Cell Line
| Catalog Number |
CBCL-0010 |
| Price |
Online Inquiry |
| Unit Quantity |
5 x 10^6 cells / 1.0 ml |
Introduction
A CHO cell line has been established to stably express the full - length human CD32a (131H) (Uniprot: P12318-1) receptor. This cell line has different levels of CD32a (131H) expression (High, Medium, Low), which can be used to test whether an agonist antibody can enhance its agonistic activity in a CD32a (131H) - dependent manner.
Application
Useful for cell-based CD32a (131H) binding assay
Background
FCGR2A encodes a receptor for the Fc region of IgG. It is widely expressed on various immune cells, including neutrophils, monocytes, macrophages, and platelets. This receptor is involved in phagocytosis, the process by which immune cells engulf and destroy pathogens or foreign particles. It also plays a role in the clearance of immune complexes and the regulation of inflammatory responses. Polymorphisms in this gene have been associated with various autoimmune and infectious diseases.
Product Information
| Category |
Fc Receptor Cell Lines |
| Cell Line Name |
CHO-Human CD32a (131H)-Medium Expression-Stable Cell Line |
| Protein Family |
Fc gamma receptor |
| Gene |
CD32a/FCGR2A |
| NCBI Gene ID |
2212 |
| Species |
Hamster |
| Host Cell Line |
CHO |
| Cell Type |
Chinese hamster ovary cell line |
| Morphology |
Epithelial |
| Growth Properties |
Adherent |
| Selection Marker |
Hygromycin B (20 μg/mL) |
| Recommended Medium |
F-12K+ 10% FBS |
| Freeze Medium |
Serum-free cell cryopreservation medium |
| Storage Method |
Frozen in liquid nitrogen. |
| Stability |
Validated for at least 10 passages |
| Mycoplasma |
Negative |
| Sterility Testing |
Negative |
| Shipping |
Shipping in dry ice |
| Biosafety Level |
BSL-1 |
| Caution |
For Research Use Only |
For research use only. Not for any other purpose.
