CHO-Human GPRC5D-Stable Cell Line

Catalog Number	CBCL-0043
Price	Online Inquiry
Unit Quantity	5 x 10^6 cells / 1.0 ml

Introduction

A stable CHO cell line expressing the human GPRC5D receptor. This cell line is useful for studying the interactions of GPRC5D with its ligands and its role in various cellular processes.

Application

Binding assay by FACS and cell based ELISA.

Background

The GPRC5D gene encodes a member of the G protein-coupled receptor family, type C, retinoid-related orphan receptor (ROR) subfamily. It is mainly expressed in the skin, hair follicles, and some immune cells. The function of GPRC5D is not well characterized, but it may be involved in cell differentiation, proliferation, and immune regulation. Recent studies have shown that GPRC5D is a potential target for cancer immunotherapy, particularly in multiple myeloma.

Product Information

Category	GPCR Cell Lines
Cell Line Name	CHO-Human GPRC5D-Stable Cell Line
Protein Family	G-protein-coupled receptor
Gene	GPRC5D
Species	Hamster
Host Cell Line	CHO
Cell Type	Chinese hamster ovary cell line
Morphology	Epithelial
Growth Properties	Adherent
Selection Marker	MSX (20 μg/mL)
Recommended Medium	OPM-CHO CDP3 medium (OPM, Cat. No. P081863-001)
Freeze Medium	10% DMSO + 90% FBS
Storage Method	Frozen in liquid nitrogen.
Stability	Validated for at least 10 passages
Mycoplasma	Negative
Sterility Testing	Negative
Shipping	Shipping in dry ice
Biosafety Level	BSL-1
Caution	For Research Use Only

For research use only. Not for any other purpose.