CHO-Human LIGHT-Stable Cell Line
| Catalog Number | CBCL-0582 |
| Price | Online Inquiry |
| Unit Quantity | 5 x 10^6 cells / 1.0 ml |
Introduction
The CHO-Human LIGHT-Stable Cell Line is engineered to express full-length human LIGHT (Uniprot: O43557-1). Surface expression of human LIGHT is confirmed by flow cytometry.
Application
Useful for cell-based LIGHT binding assay
Background
LIGHT (TNFSF14) is a co-stimulatory molecule expressed on activated T cells and NK cells. It binds to HVEM (TNFRSF14) and LTβR, promoting lymphocyte activation, cytokine production, and tissue inflammation. LIGHT signaling is implicated in autoimmune diseases and cancer immunotherapy.
Product Information
| Category | Immune Checkpoint Cell Lines |
| Cell Line Name | CHO-Human LIGHT-Stable Cell Line |
| Protein Family | TNF superfamily |
| Gene | LIGHT |
| Species | Hamster |
| Host Cell Line | CHO |
| Cell Type | Chinese hamster ovary cell line |
| Morphology | Epithelial |
| Growth Properties | Adherent |
| Selection Marker | Puromycin (2 μg/mL) |
| Recommended Medium | F-12K + 10% FBS |
| Freeze Medium | Serum-free cell cryopreservation medium |
| Storage Method | Frozen in liquid nitrogen. |
| Stability | Validated for at least 10 passages |
| Mycoplasma | Negative |
| Sterility Testing | Negative |
| Shipping | Shipping in dry ice |
| Biosafety Level | BSL-1 |
| Caution | For Research Use Only |
For research use only. Not for any other purpose.