| Catalog Number | CBCL-0582 |
| Price | Online Inquiry |
| Unit Quantity | 5 x 10^6 cells / 1.0 ml |
The CHO-Human LIGHT-Stable Cell Line is engineered to express full-length human LIGHT (Uniprot: O43557-1). Surface expression of human LIGHT is confirmed by flow cytometry.
Useful for cell-based LIGHT binding assay
LIGHT (TNFSF14) is a co-stimulatory molecule expressed on activated T cells and NK cells. It binds to HVEM (TNFRSF14) and LTβR, promoting lymphocyte activation, cytokine production, and tissue inflammation. LIGHT signaling is implicated in autoimmune diseases and cancer immunotherapy.
| Category | Immune Checkpoint Cell Lines |
| Cell Line Name | CHO-Human LIGHT-Stable Cell Line |
| Protein Family | TNF superfamily |
| Gene | LIGHT |
| Species | Hamster |
| Host Cell Line | CHO |
| Cell Type | Chinese hamster ovary cell line |
| Morphology | Epithelial |
| Growth Properties | Adherent |
| Selection Marker | Puromycin (2 μg/mL) |
| Recommended Medium | F-12K + 10% FBS |
| Freeze Medium | Serum-free cell cryopreservation medium |
| Storage Method | Frozen in liquid nitrogen. |
| Stability | Validated for at least 10 passages |
| Mycoplasma | Negative |
| Sterility Testing | Negative |
| Shipping | Shipping in dry ice |
| Biosafety Level | BSL-1 |
| Caution | For Research Use Only |