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CHO-Human LIGHT-Stable Cell Line

Catalog Number CBCL-0582
Price Online Inquiry
Unit Quantity 5 x 10^6 cells / 1.0 ml

Introduction

The CHO-Human LIGHT-Stable Cell Line is engineered to express full-length human LIGHT (Uniprot: O43557-1). Surface expression of human LIGHT is confirmed by flow cytometry.

Application

Useful for cell-based LIGHT binding assay

Background

LIGHT (TNFSF14) is a co-stimulatory molecule expressed on activated T cells and NK cells. It binds to HVEM (TNFRSF14) and LTβR, promoting lymphocyte activation, cytokine production, and tissue inflammation. LIGHT signaling is implicated in autoimmune diseases and cancer immunotherapy.

Product Information

Category Immune Checkpoint Cell Lines
Cell Line Name CHO-Human LIGHT-Stable Cell Line
Protein Family TNF superfamily
Gene LIGHT
Species Hamster
Host Cell Line CHO
Cell Type Chinese hamster ovary cell line
Morphology Epithelial
Growth Properties Adherent
Selection Marker Puromycin (2 μg/mL)
Recommended Medium F-12K + 10% FBS
Freeze Medium Serum-free cell cryopreservation medium
Storage Method Frozen in liquid nitrogen.
Stability Validated for at least 10 passages
Mycoplasma Negative
Sterility Testing Negative
Shipping Shipping in dry ice
Biosafety Level BSL-1
Caution For Research Use Only
For research use only. Not for any other purpose.
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