| Catalog Number | CBCL-0563 |
| Price | Online Inquiry |
| Unit Quantity | 1 x 10^6 cells / 1.0 ml |
The CHO-K1-B7-H2-Stable Cell Line consists of recombinant CHO-K1 cells that stably overexpress human B7-H2 on their surface.
Drug screening and biological assays
B7-H2 (ICOS Ligand, TNFSF18) is a co-stimulatory molecule expressed on antigen-presenting cells (APCs). It binds to ICOS on T cells, promoting T cell activation, cytokine production, and B cell help. B7-H2 is essential for germinal center responses and antibody production.
| Category | Immune Checkpoint Cell Lines |
| Cell Line Name | CHO-K1-B7H2-Stable Cell Line |
| Protein Family | B7 family |
| Gene | B7-H2 |
| Species | Hamster |
| Host Cell Line | CHOK1 |
| Cell Type | Chinese hamster ovary cell line |
| Morphology | Epithelial |
| Growth Properties | Adherent |
| Recommended Medium | F12K, 10% FBS, 8 μg/ml Puromycin |
| Freeze Medium | 95% complete growth medium + 5% DMSO |
| Storage Method | Frozen in liquid nitrogen. |
| Stability | Validated for at least 10 passages |
| Mycoplasma | Negative |
| Sterility Testing | Negative |
| Shipping | Shipping in dry ice |
| Biosafety Level | BSL-1 |
| Caution | For Research Use Only |