CHO-K1-B7H4-Stable Cell Line
| Catalog Number | CBCL-0565 |
| Price | Online Inquiry |
| Unit Quantity | 1 x 10^6 cells / 1.0 ml |
Introduction
The CHO-K1-B7-H4-Stable Cell Line consists of recombinant CHO-K1 cells that stably overexpress human B7-H4 on their surface.
Application
Drug screening and biological assays
Background
B7-H4 (VTCN1) is an inhibitory immune checkpoint molecule expressed on tumor cells and macrophages. It suppresses T cell proliferation and cytokine production by inhibiting TCR signaling. B7-H4 overexpression correlates with poor cancer prognosis and immune suppression.
Product Information
| Category | Immune Checkpoint Cell Lines |
| Cell Line Name | CHO-K1-B7H4-Stable Cell Line |
| Protein Family | Immunoglobulin superfamily |
| Gene | B7-H4 |
| Species | Hamster |
| Host Cell Line | CHOK1 |
| Cell Type | Chinese hamster ovary cell line |
| Morphology | Epithelial |
| Growth Properties | Adherent |
| Storage Method | Frozen in liquid nitrogen. |
| Stability | Validated for at least 10 passages |
| Mycoplasma | Negative |
| Sterility Testing | Negative |
| Shipping | Shipping in dry ice |
| Caution | For Research Use Only |
For research use only. Not for any other purpose.