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CHO-K1-BTLA-Stable Cell Line

Catalog Number CBCL-0543
Price Online Inquiry
Unit Quantity 1 x 10^6 cells / 1.0 ml

Introduction

The CHO-K1-BTLA-Stable Cell Line consists of recombinant CHO-K1 cells that stably overexpress human B and T lymphocyte associated (BTLA) on their surface. The surface expression of BTLA is confirmed by FACS analysis.

Application

Drug screening and biological assays

Background

BTLA (B and T Lymphocyte Attenuator) is an immune checkpoint receptor expressed on T cells, B cells, and NK cells. It binds to HVEM (TNFRSF14) and delivers inhibitory signals that suppress lymphocyte activation. BTLA synergizes with PD-1 to promote immune tolerance.

Product Information

Category Immune Checkpoint Cell Lines
Cell Line Name CHO-K1-BTLA-Stable Cell Line
Protein Family B and T lymphocyte attenuator family
Gene BTLA
Species Hamster
Host Cell Line CHOK1
Cell Type Chinese hamster ovary cell line
Morphology Epithelial
Growth Properties Adherent
Storage Method Frozen in liquid nitrogen.
Stability Validated for at least 10 passages
Mycoplasma Negative
Sterility Testing Negative
Shipping Shipping in dry ice
Caution For Research Use Only
For research use only. Not for any other purpose.