CHO-K1-CCKB-Stable Cell Line
| Catalog Number | CBCL-0090 |
| Price | Online Inquiry |
| Unit Quantity | 1 x 10^6 cells / 1.0 ml |
Introduction
The Human Recombinant CHO-K1/CCKB Stable Cell Line has been designed to stably overexpress the Cholecystokinin Receptor gene (CCKB). This stable cell line is intended for measuring the in vitro function of CCKB.
Application
Drug screening and biological assays
Background
The CCKB gene, also known as CCKBR, encodes the cholecystokinin B receptor, a G protein - coupled receptor. It is widely distributed in the central nervous system and the gastrointestinal tract. In the brain, activation of CCKBR by CCK is involved in regulating anxiety, pain perception, and appetite. In the gastrointestinal tract, it regulates gastric acid secretion, gastric emptying, and intestinal motility.
Product Information
| Category | GPCR Cell Lines |
| Cell Line Name | CHO-K1-CCKB-Stable Cell Line |
| Protein Family | Cholecystokinin receptor |
| Gene | CCKB/CCKBR |
| NCBI Gene ID | 887 |
| Species | Hamster |
| Host Cell Line | CHOK1 |
| Cell Type | Chinese hamster ovary cell line |
| Morphology | Epithelial |
| Growth Properties | Adherent |
| Recommended Medium | Ham’s F-12K (Kaighn’s), 10% FBS, 200 μg/ml Zeocin |
| Freeze Medium | 45% culture medium + 45% FBS + 10% DMSO |
| Storage Method | Frozen in liquid nitrogen. |
| Stability | Validated for at least 10 passages |
| Mycoplasma | Negative |
| Sterility Testing | Negative |
| Shipping | Shipping in dry ice |
| Biosafety Level | BSL-1 |
| Caution | For Research Use Only |
For research use only. Not for any other purpose.