CHO-K1-CCKB-Stable Cell Line

Catalog Number	CBCL-0090
Price	Online Inquiry
Unit Quantity	1 x 10^6 cells / 1.0 ml

Introduction

The Human Recombinant CHO-K1/CCKB Stable Cell Line has been designed to stably overexpress the Cholecystokinin Receptor gene (CCKB). This stable cell line is intended for measuring the in vitro function of CCKB.

Application

Drug screening and biological assays

Background

The CCKB gene, also known as CCKBR, encodes the cholecystokinin B receptor, a G protein - coupled receptor. It is widely distributed in the central nervous system and the gastrointestinal tract. In the brain, activation of CCKBR by CCK is involved in regulating anxiety, pain perception, and appetite. In the gastrointestinal tract, it regulates gastric acid secretion, gastric emptying, and intestinal motility.

Product Information

Category	GPCR Cell Lines
Cell Line Name	CHO-K1-CCKB-Stable Cell Line
Protein Family	Cholecystokinin receptor
Gene	CCKB/CCKBR
NCBI Gene ID	887
Species	Hamster
Host Cell Line	CHOK1
Cell Type	Chinese hamster ovary cell line
Morphology	Epithelial
Growth Properties	Adherent
Recommended Medium	Ham’s F-12K (Kaighn’s), 10% FBS, 200 μg/ml Zeocin
Freeze Medium	45% culture medium + 45% FBS + 10% DMSO
Storage Method	Frozen in liquid nitrogen.
Stability	Validated for at least 10 passages
Mycoplasma	Negative
Sterility Testing	Negative
Shipping	Shipping in dry ice
Biosafety Level	BSL-1
Caution	For Research Use Only

For research use only. Not for any other purpose.