CHO-K1-CD155-Stable Cell Line
| Catalog Number |
CBCL-0553 |
| Price |
Online Inquiry |
| Unit Quantity |
1 x 10^6 cells / 1.0 ml |
Introduction
The CHO-K1-CD155-Stable Cell Line consists of recombinant CHO-K1 cells that stably overexpress Homo sapiens PVR cell adhesion molecule (CD155) on their surface. The surface expression of CD155 is confirmed by FACS analysis.
Application
Drug screening and biological assays
Background
CD155 (PVR, Poliovirus Receptor) is a transmembrane protein expressed on epithelial cells and tumor cells. It binds to DNAM-1 (activating) and TIGIT/CD96 (inhibitory) receptors on immune cells, modulating cytotoxicity and immune escape. CD155 overexpression is associated with poor cancer prognosis.
Product Information
| Category |
Immune Checkpoint Cell Lines |
| Cell Line Name |
CHO-K1-CD155-Stable Cell Line |
| Protein Family |
Nectin family |
| Gene |
CD155 |
| NCBI Gene ID |
5817 |
| Species |
Hamster |
| Host Cell Line |
CHOK1 |
| Cell Type |
Chinese hamster ovary cell line |
| Morphology |
Epithelial |
| Growth Properties |
Adherent |
| Recommended Medium |
Ham’s F-12K (Kaighn’s), 10% FBS, 8 μg/ml Puromycin |
| Freeze Medium |
95% complete growth medium + 5% DMSO |
| Storage Method |
Frozen in liquid nitrogen. |
| Stability |
Validated for at least 10 passages |
| Mycoplasma |
Negative |
| Sterility Testing |
Negative |
| Shipping |
Shipping in dry ice |
| Biosafety Level |
BSL-1 |
| Caution |
For Research Use Only |
For research use only. Not for any other purpose.
