CHO-K1-CD80-Stable Cell Line
| Catalog Number |
CBCL-0550 |
| Price |
Online Inquiry |
| Unit Quantity |
1 x 10^6 cells / 1.0 ml |
Introduction
The CHO-K1-CD80-Stable Cell Line consists of recombinant CHO-K1 cells that stably overexpress human CD80 on their surface. The surface expression of CD80 is confirmed by FACS analysis.
Application
Drug screening and biological assays
Background
CD80 (B7-1) is a co-stimulatory molecule expressed on antigen-presenting cells (APCs). It binds to CD28 on T cells to promote activation, or to CTLA-4 to deliver inhibitory signals. CD80/CD86-CD28/CTLA-4 axis is critical for immune tolerance and autoimmunity.
Product Information
| Category |
Immune Checkpoint Cell Lines |
| Cell Line Name |
CHO-K1-CD80-Stable Cell Line |
| Protein Family |
B7 family |
| Gene |
CD80 |
| NCBI Gene ID |
941 |
| Species |
Hamster |
| Host Cell Line |
CHOK1 |
| Cell Type |
Chinese hamster ovary cell line |
| Morphology |
Epithelial |
| Growth Properties |
Adherent |
| Recommended Medium |
Ham’s F-12K (Kaighn’s), 10% FBS, 4 μg/ml Puromycin |
| Freeze Medium |
95% complete growth medium + 5% DMSO |
| Storage Method |
Frozen in liquid nitrogen. |
| Stability |
Validated for at least 10 passages |
| Mycoplasma |
Negative |
| Sterility Testing |
Negative |
| Shipping |
Shipping in dry ice |
| Biosafety Level |
BSL-1 |
| Caution |
For Research Use Only |
For research use only. Not for any other purpose.
