CHO-K1-CRF1/Gα15-Stable Cell Line
| Catalog Number | CBCL-0093 |
| Price | Online Inquiry |
| Unit Quantity | 1 x 10^6 cells / 1.0 ml |
Introduction
A CHO-K1 cell line has been engineered to stably overexpress human corticotropin releasing hormone receptor 1 (CRF1) on its surface. This cell line contains high levels of the G protein Gαs, which is essential for coupling with the receptor in downstream signaling pathways.
Application
Drug screening and biological assays
Background
Corticotropin Releasing Hormone Receptor 1 (CRHR1) is a G protein-coupled receptor that binds corticotropin-releasing hormone (CRH) and related peptides, playing a crucial role in the stress response and regulation of the hypothalamic-pituitary-adrenal axis.
Product Information
| Category | GPCR Cell Lines |
| Cell Line Name | CHO-K1-CRF1/Gα15-Stable Cell Line |
| Protein Family | Corticotropin releasing factor receptor |
| Gene | CRF1/CRHR1 |
| NCBI Gene ID | 1394 |
| Species | Hamster |
| Host Cell Line | CHOK1 |
| Cell Type | Chinese hamster ovary cell line |
| Morphology | Epithelial |
| Growth Properties | Adherent |
| Storage Method | Frozen in liquid nitrogen. |
| Stability | Validated for at least 10 passages |
| Mycoplasma | Negative |
| Sterility Testing | Negative |
| Shipping | Shipping in dry ice |
| Caution | For Research Use Only |
For research use only. Not for any other purpose.