CHO-K1-cyno 4-1BB-Stable Cell Line
| Catalog Number | CBCL-0559 |
| Price | Online Inquiry |
| Unit Quantity | 1 x 10^6 cells / 1.0 ml |
Introduction
The CHO-K1-cyno 4-1BB-Stable Cell Line consists of recombinant CHO-K1 cells that stably overexpress cynomolgus TNF receptor superfamily member 9 (4-1BB) on their surface.
Application
Drug screening and biological assays
Background
4-1BB (TNFRSF9, CD137) is a co-stimulatory receptor expressed on activated T cells, NK cells, and dendritic cells. It binds to 4-1BB Ligand (TNFSF9) on APCs, promoting T cell proliferation, survival, and cytokine production. 4-1BB agonists are being tested in cancer immunotherapy.
Product Information
| Category | Immune Checkpoint Cell Lines |
| Cell Line Name | CHO-K1-cyno 4-1BB-Stable Cell Line |
| Protein Family | TNF receptor superfamily |
| Gene | 4-1BB |
| NCBI Gene ID | 3604 |
| Species | Hamster |
| Host Cell Line | CHOK1 |
| Cell Type | Chinese hamster ovary cell line |
| Morphology | Epithelial |
| Growth Properties | Adherent |
| Storage Method | Frozen in liquid nitrogen. |
| Stability | Validated for at least 10 passages |
| Mycoplasma | Negative |
| Sterility Testing | Negative |
| Shipping | Shipping in dry ice |
| Caution | For Research Use Only |
For research use only. Not for any other purpose.