CHO-K1-Cyno BDCA2 and FcER1G-Stable Cell Line
| Catalog Number |
CBCL-0542 |
| Price |
Online Inquiry |
| Unit Quantity |
1 x 10^6 cells / 1.0 ml |
Introduction
The CHO-K1-Cyno BDCA2 and FcER1G-Stable Cell Line consists of recombinant CHO-K1 cells that stably overexpress Macaca fascicularis C-type lectin domain family 4 member C (BDCA2) and Fc epsilon receptor Ig (FcER1G) on their surface. The surface expression of BDCA2 is confirmed by FACS analysis.
Application
Drug screening and biological assays
Background
BDCA2 (Blood Dendritic Cell Antigen 2) is a C-type lectin receptor expressed on plasmacytoid dendritic cells (pDCs). It regulates pDC activation by inhibiting TLR-induced cytokine production (e.g., IFN-α). BDCA2 is a target for autoimmune disease therapy (e.g., systemic lupus erythematosus).
Product Information
| Category |
Immune Checkpoint Cell Lines |
| Cell Line Name |
CHO-K1-Cyno BDCA2 and FcER1G-Stable Cell Line |
| Protein Family |
C-type lectin receptor family |
| Gene |
BDCA2; FcER1G |
| Species |
Hamster |
| Host Cell Line |
CHOK1 |
| Cell Type |
Chinese hamster ovary cell line |
| Morphology |
Epithelial |
| Growth Properties |
Adherent |
| Recommended Medium |
Ham’s F-12K (Kaighn’s), 10% FBS, 4 μg/ml Puromycin |
| Freeze Medium |
95% complete growth medium + 5% DMSO |
| Storage Method |
Frozen in liquid nitrogen. |
| Stability |
Validated for at least 10 passages |
| Mycoplasma |
Negative |
| Sterility Testing |
Negative |
| Shipping |
Shipping in dry ice |
| Biosafety Level |
BSL-1 |
| Caution |
For Research Use Only |
For research use only. Not for any other purpose.
