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CHO-K1-Cyno BDCA2-Stable Cell Line

Catalog Number CBCL-0540
Price Online Inquiry
Unit Quantity 1 x 10^6 cells / 1.0 ml

Introduction

The CHO-K1-Cyno BDCA2-Stable Cell Line consists of recombinant CHO-K1 cells that stably overexpress cynomolgus C-type lectin domain family 4 member C (BDCA2) on their surface.

Application

Drug screening and biological assays

Background

BDCA2 (Blood Dendritic Cell Antigen 2) is a C-type lectin receptor expressed on plasmacytoid dendritic cells (pDCs). It regulates pDC activation by inhibiting TLR-induced cytokine production (e.g., IFN-α). BDCA2 is a target for autoimmune disease therapy (e.g., systemic lupus erythematosus).

Product Information

Category Immune Checkpoint Cell Lines
Cell Line Name CHO-K1-Cyno BDCA2-Stable Cell Line
Protein Family C-type lectin receptor family
Gene BDCA2
Species Hamster
Host Cell Line CHOK1
Cell Type Chinese hamster ovary cell line
Morphology Epithelial
Growth Properties Adherent
Storage Method Frozen in liquid nitrogen.
Stability Validated for at least 10 passages
Mycoplasma Negative
Sterility Testing Negative
Shipping Shipping in dry ice
Caution For Research Use Only
For research use only. Not for any other purpose.