| Catalog Number | CBCL-0568 |
| Price | Online Inquiry |
| Unit Quantity | 1 x 10^6 cells / 1.0 ml |
The CHO-K1-Cyno HVEM-Stable Cell Line consists of recombinant CHO-K1 cells that stably overexpress cynomolgus HVEM on their surface.
Drug screening and biological assays
HVEM (Herpesvirus Entry Mediator, TNFRSF14) is a dual-function receptor expressed on immune cells. It binds to LIGHT (TNFSF14, activating) or BTLA/CD162 (inhibitory), modulating lymphocyte activation and immune tolerance. HVEM is involved in autoimmune diseases and tumor immune evasion.
| Category | Immune Checkpoint Cell Lines |
| Cell Line Name | CHO-K1-Cyno HVEM-Stable Cell Line |
| Protein Family | TNF receptor superfamily |
| Gene | HVEM |
| Species | Hamster |
| Host Cell Line | CHOK1 |
| Cell Type | Chinese hamster ovary cell line |
| Morphology | Epithelial |
| Growth Properties | Adherent |
| Recommended Medium | F12K, 10% FBS, 8 μg/ml Puromycin |
| Freeze Medium | 95% complete growth medium + 5% DMSO |
| Storage Method | Frozen in liquid nitrogen. |
| Stability | Validated for at least 10 passages |
| Mycoplasma | Negative |
| Sterility Testing | Negative |
| Shipping | Shipping in dry ice |
| Biosafety Level | BSL-1 |
| Caution | For Research Use Only |