CHO-K1-Cyno VISTA-Stable Cell Line
| Catalog Number |
CBCL-0538 |
| Price |
Online Inquiry |
| Unit Quantity |
1 x 10^6 cells / 1.0 ml |
Introduction
The CHO-K1-Cyno VISTA-Stable Cell Line consists of recombinant CHO-K1 cells that stably overexpress Macaca fascicularis V-set immunoregulatory receptor (VISTA) on their surface. The surface expression of cyno VISTA is confirmed by FACS analysis.
Application
Drug screening and biological assays
Background
VISTA (V-domain Ig suppressor of T cell activation) is an immune checkpoint protein expressed on hematopoietic cells and tumor cells. It functions as a ligand for multiple receptors (e.g., PSGL-1) and suppresses T cell activation by inhibiting TCR signaling. VISTA is overexpressed in various cancers and correlates with poor prognosis.
Product Information
| Category |
Immune Checkpoint Cell Lines |
| Cell Line Name |
CHO-K1-Cyno VISTA-Stable Cell Line |
| Protein Family |
V-domain Ig suppressor of T cell activation family |
| Gene |
VISTA |
| Species |
Hamster |
| Host Cell Line |
CHOK1 |
| Cell Type |
Chinese hamster ovary cell line |
| Morphology |
Epithelial |
| Growth Properties |
Adherent |
| Recommended Medium |
Ham’s F-12K (Kaighn’s), 10% FBS, 11 μg/ml Puromycin |
| Freeze Medium |
95% complete growth medium + 5% DMSO |
| Storage Method |
Frozen in liquid nitrogen. |
| Stability |
Validated for at least 10 passages |
| Mycoplasma |
Negative |
| Sterility Testing |
Negative |
| Shipping |
Shipping in dry ice |
| Biosafety Level |
BSL-1 |
| Caution |
For Research Use Only |
For research use only. Not for any other purpose.
