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CHO-K1-CysLT1/Gα15-Stable Cell Line

Catalog Number CBCL-0117
Price Online Inquiry
Unit Quantity 1 x 10^6 cells / 1.0 ml

Introduction

The CHO-K1-CysLT1/Gα15-Stable Cell Line is designed to stably express the CysLT1 receptor along with the Gα15 protein. This setup allows for the investigation of CysLT1-mediated signaling pathways.

Application

Drug screening and biological assays

Background

Cysteinyl leukotriene receptor 1 (CysLT1) is a G protein-coupled receptor that binds cysteinyl leukotrienes, potent mediators of inflammation and bronchoconstriction, and is involved in asthma and allergic responses.

Product Information

Category GPCR Cell Lines
Cell Line Name CHO-K1-CysLT1/Gα15-Stable Cell Line
Protein Family Leukotriene receptor
Gene CysLT1
Species Hamster
Host Cell Line CHOK1
Cell Type Chinese hamster ovary cell line
Morphology Epithelial
Growth Properties Adherent
Recommended Medium Ham’s F-12K (Kaighn’s), 10% FBS, 400 μg/ml Geneticin, 100 μg/ml Hygromycin B
Freeze Medium 45% culture medium + 45% FBS + 10% DMSO
Storage Method Frozen in liquid nitrogen.
Stability Validated for at least 10 passages
Mycoplasma Negative
Sterility Testing Negative
Shipping Shipping in dry ice
Biosafety Level BSL-1
Caution For Research Use Only
For research use only. Not for any other purpose.
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