CHO-K1-D2s/Gα15-Stable Cell Line
| Catalog Number | CBCL-0096 |
| Price | Online Inquiry |
| Unit Quantity | 1 x 10^6 cells / 1.0 ml |
Introduction
A CHO-K1 cell line has been engineered to stably overexpress human dopamine receptor D2s (D2s) on its surface. This cell line contains high levels of the G protein Gαi, which is crucial for coupling with the receptor in downstream signaling pathways. This variant encodes a 414 aa isoform (short), which is 29 aa shorter than the long one.
Application
Drug screening and biological assays
Background
Dopamine Receptor D2 short form (DRD2s) is a variant of the dopamine receptor D2, which is implicated in conditions such as schizophrenia and Parkinson's disease.
Product Information
| Category | GPCR Cell Lines |
| Cell Line Name | CHO-K1-D2s/Gα15-Stable Cell Line |
| Protein Family | Dopamine receptor |
| Gene | D2s/DRD2 |
| NCBI Gene ID | 1813 |
| Species | Hamster |
| Host Cell Line | CHOK1 |
| Cell Type | Chinese hamster ovary cell line |
| Morphology | Epithelial |
| Growth Properties | Adherent |
| Storage Method | Frozen in liquid nitrogen. |
| Stability | Validated for at least 10 passages |
| Mycoplasma | Negative |
| Sterility Testing | Negative |
| Shipping | Shipping in dry ice |
| Caution | For Research Use Only |
For research use only. Not for any other purpose.