CHO-K1-DAT-Recombinant Cell Line
| Catalog Number |
CBCL-0667 |
| Price |
Online Inquiry |
| Unit Quantity |
2 x 10^6 cells / 1.0 ml |
Introduction
A recombinant CHO-K1 cell line engineered to express the human sodium-dependent dopamine transporter (DAT), with Genbank accession number NM_001044.
Application
Drug screening and biological assays
Background
Dopamine transporter (DAT), also known as SLC6A3, is a membrane-spanning protein that plays a crucial role in the reuptake of dopamine from the synaptic cleft back into presynaptic neurons. This process is essential for terminating dopaminergic neurotransmission and maintaining appropriate levels of dopamine in the brain. DAT is a target for various drugs, including cocaine and amphetamines, which can alter its function and lead to changes in mood, behavior, and reward processing.
Product Information
| Category |
Ion Channel Cell Lines |
| Cell Line Name |
CHO-K1-DAT-Recombinant Cell Line |
| Protein Family |
Dopamine transporter family |
| Gene |
DAT |
| NCBI Gene ID |
6531 |
| Species |
Hamster |
| Host Cell Line |
CHO |
| Cell Type |
Chinese hamster ovary cell line |
| Morphology |
Epithelial |
| Growth Properties |
Adherent |
| Recommended Medium |
F-12K + 10% FBS |
| Freeze Medium |
10% DMSO |
| Storage Method |
Frozen in liquid nitrogen. |
| Stability |
Validated for at least 10 passages |
| Mycoplasma |
Negative |
| Sterility Testing |
Negative |
| Shipping |
Shipping in dry ice |
| Biosafety Level |
BSL-1 |
| Caution |
For Research Use Only |
For research use only. Not for any other purpose.
