CHO-K1-EDNRB-Stable Cell Line
| Catalog Number |
CBCL-0100 |
| Price |
Online Inquiry |
| Unit Quantity |
1 x 10^6 cells / 1.0 ml |
Introduction
A CHO-K1 cell line has been engineered to stably overexpress human endothelin receptor type B (EDNRB) on its surface. This cell line contains high levels of the G protein Gαq, which is essential for coupling with the receptor in downstream signaling pathways.
Application
Drug screening and biological assays
Background
Endothelin Receptor B (EDNRB) is another receptor for endothelin, with functions similar to EDNRA but with different distribution and effects. It is involved in various physiological processes, including vascular tone regulation and neural crest cell development.
Product Information
| Category |
GPCR Cell Lines |
| Cell Line Name |
CHO-K1-EDNRB-Stable Cell Line |
| Protein Family |
Endothelin receptor |
| Gene |
ETB/EDNRB |
| NCBI Gene ID |
1910 |
| Species |
Hamster |
| Host Cell Line |
CHOK1 |
| Cell Type |
Chinese hamster ovary cell line |
| Morphology |
Epithelial |
| Growth Properties |
Adherent |
| Recommended Medium |
Ham’s F-12K (Kaighn’s), 10% FBS, 200 μg/ml Zeocin |
| Freeze Medium |
45% culture medium + 45% FBS + 10% DMSO |
| Storage Method |
Frozen in liquid nitrogen. |
| Stability |
Validated for at least 10 passages |
| Mycoplasma |
Negative |
| Sterility Testing |
Negative |
| Shipping |
Shipping in dry ice |
| Biosafety Level |
BSL-1 |
| Caution |
For Research Use Only |
For research use only. Not for any other purpose.
