CHO-K1-FFA1/Gα15-Stable Cell Line
| Catalog Number | CBCL-0102 |
| Price | Online Inquiry |
| Unit Quantity | 1 x 10^6 cells / 1.0 ml |
Introduction
A CHO-K1 cell line has been created to stably overexpress human free fatty acid receptor 1 (FFA1) on its surface. This cell line contains high levels of the G protein Gαq, which is essential for coupling with the receptor in downstream signaling pathways.
Application
Drug screening and biological assays
Background
G protein-coupled receptor 40 (GPR40), also known as free fatty acid receptor 1 (FFA1), is a receptor for medium- and long-chain free fatty acids. It is expressed in pancreatic beta cells and plays a key role in regulating insulin secretion in response to increased plasma fatty acid levels.
Product Information
| Category | GPCR Cell Lines |
| Cell Line Name | CHO-K1-FFA1/Gα15-Stable Cell Line |
| Protein Family | Free fatty acid receptor |
| Gene | GPR40/FFA1 |
| NCBI Gene ID | 2864 |
| Species | Hamster |
| Host Cell Line | CHOK1 |
| Cell Type | Chinese hamster ovary cell line |
| Morphology | Epithelial |
| Growth Properties | Adherent |
| Storage Method | Frozen in liquid nitrogen. |
| Stability | Validated for at least 10 passages |
| Mycoplasma | Negative |
| Sterility Testing | Negative |
| Shipping | Shipping in dry ice |
| Caution | For Research Use Only |
For research use only. Not for any other purpose.