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CHO-K1-GHSR-Stable Cell Line

Catalog Number CBCL-0105
Price Online Inquiry
Unit Quantity 1 x 10^6 cells / 1.0 ml

Introduction

Recombinant CHO-K1 cells have been designed to stably overexpress the human growth hormone secretagogue receptor (GHSR) on their surface, and they contain high levels of the G protein Gαq, which is involved in coupling with the receptor to facilitate downstream signaling pathways.

Application

Drug screening and biological assays

Background

Growth hormone secretagogue receptor (GHSR) is a G protein-coupled receptor that binds ghrelin, a peptide hormone that stimulates growth hormone release and regulates appetite and energy balance.

Product Information

Category GPCR Cell Lines
Cell Line Name CHO-K1-GHSR-Stable Cell Line
Protein Family Ghrelin receptor
Gene GHSR
NCBI Gene ID 2693
Species Hamster
Host Cell Line CHOK1
Cell Type Chinese hamster ovary cell line
Morphology Epithelial
Growth Properties Adherent
Recommended Medium Ham’s F-12K (Kaighn’s), 10% FBS, 500 μg/ml G418
Freeze Medium 45% culture medium + 45% FBS + 10% DMSO
Storage Method Frozen in liquid nitrogen.
Stability Validated for at least 10 passages
Mycoplasma Negative
Sterility Testing Negative
Shipping Shipping in dry ice
Biosafety Level BSL-1
Caution For Research Use Only
For research use only. Not for any other purpose.
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