CHO-K1-GITR-Stable Cell Line
| Catalog Number |
CBCL-0561 |
| Price |
Online Inquiry |
| Unit Quantity |
1 x 10^6 cells / 1.0 ml |
Introduction
The CHO-K1-GITR-Stable Cell Line consists of recombinant CHO-K1 cells that stably overexpress human glucocorticoid-induced TNFR-related protein (GITR) on their surface.
Application
Drug screening and biological assays
Background
GITR (Glucocorticoid-Induced TNFR-Related Protein) is a co-stimulatory receptor expressed on regulatory T cells (Tregs) and activated T cells. It binds to GITR Ligand (TNFSF18), promoting T cell proliferation and suppressing Treg function. GITR agonists are being explored for cancer immunotherapy.
Product Information
| Category |
Immune Checkpoint Cell Lines |
| Cell Line Name |
CHO-K1-GITR-Stable Cell Line |
| Protein Family |
TNF receptor superfamily |
| Gene |
GITR |
| NCBI Gene ID |
8784 |
| Species |
Hamster |
| Host Cell Line |
CHOK1 |
| Cell Type |
Chinese hamster ovary cell line |
| Morphology |
Epithelial |
| Growth Properties |
Adherent |
| Recommended Medium |
F12K, 10% FBS, 6 μg/ml Puromycin |
| Freeze Medium |
95% complete growth medium + 5% DMSO |
| Storage Method |
Frozen in liquid nitrogen. |
| Stability |
Validated for at least 10 passages |
| Mycoplasma |
Negative |
| Sterility Testing |
Negative |
| Shipping |
Shipping in dry ice |
| Biosafety Level |
BSL-1 |
| Caution |
For Research Use Only |
For research use only. Not for any other purpose.
