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CHO-K1-ICOS-Stable Cell Line

Catalog Number CBCL-0562
Price Online Inquiry
Unit Quantity 1 x 10^6 cells / 1.0 ml

Introduction

The CHO-K1-ICOS-Stable Cell Line consists of recombinant CHO-K1 cells that stably overexpress Homo sapiens inducible T cell costimulator (ICOS) on their surface. The surface expression of ICOS is confirmed by FACS analysis.

Application

Drug screening and biological assays

Background

ICOS (Inducible T Cell Costimulator) is a co-stimulatory receptor expressed on activated T cells. It binds to ICOS Ligand (B7-H2, TNFSF18) on APCs, promoting T cell proliferation, cytokine production, and B cell help. ICOS is critical for germinal center formation and humoral immunity.

Product Information

Category Immune Checkpoint Cell Lines
Cell Line Name CHO-K1-ICOS-Stable Cell Line
Protein Family Inducible T-cell COStimulator family
Gene ICOS
Species Hamster
Host Cell Line CHOK1
Cell Type Chinese hamster ovary cell line
Morphology Epithelial
Growth Properties Adherent
Storage Method Frozen in liquid nitrogen.
Stability Validated for at least 10 passages
Mycoplasma Negative
Sterility Testing Negative
Shipping Shipping in dry ice
Caution For Research Use Only
For research use only. Not for any other purpose.