CHO-K1-ICOS-Stable Cell Line
| Catalog Number |
CBCL-0562 |
| Price |
Online Inquiry |
| Unit Quantity |
1 x 10^6 cells / 1.0 ml |
Introduction
The CHO-K1-ICOS-Stable Cell Line consists of recombinant CHO-K1 cells that stably overexpress Homo sapiens inducible T cell costimulator (ICOS) on their surface. The surface expression of ICOS is confirmed by FACS analysis.
Application
Drug screening and biological assays
Background
ICOS (Inducible T Cell Costimulator) is a co-stimulatory receptor expressed on activated T cells. It binds to ICOS Ligand (B7-H2, TNFSF18) on APCs, promoting T cell proliferation, cytokine production, and B cell help. ICOS is critical for germinal center formation and humoral immunity.
Product Information
| Category |
Immune Checkpoint Cell Lines |
| Cell Line Name |
CHO-K1-ICOS-Stable Cell Line |
| Protein Family |
Inducible T-cell COStimulator family |
| Gene |
ICOS |
| Species |
Hamster |
| Host Cell Line |
CHOK1 |
| Cell Type |
Chinese hamster ovary cell line |
| Morphology |
Epithelial |
| Growth Properties |
Adherent |
| Recommended Medium |
Ham’s F-12K (Kaighn’s), 10% FBS, 8 μg/ml Puromycin |
| Freeze Medium |
95% complete growth medium + 5% DMSO |
| Storage Method |
Frozen in liquid nitrogen. |
| Stability |
Validated for at least 10 passages |
| Mycoplasma |
Negative |
| Sterility Testing |
Negative |
| Shipping |
Shipping in dry ice |
| Biosafety Level |
BSL-1 |
| Caution |
For Research Use Only |
For research use only. Not for any other purpose.
