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CHO-K1-KIR-Stable Cell Line

Catalog Number CBCL-0544
Price Online Inquiry
Unit Quantity 1 x 10^6 cells / 1.0 ml

Introduction

The CHO-K1-KIR-Stable Cell Line consists of recombinant CHO-K1 cells that stably overexpress human killer cell immunoglobulin-like receptor (KIR) on their surface.

Application

Drug screening and biological assays

Background

KIR (Killer-cell Immunoglobulin-like Receptors) are a family of inhibitory/activating receptors expressed on NK cells and some T cells. They recognize MHC class I molecules and regulate NK cell-mediated cytotoxicity. KIR polymorphisms influence susceptibility to infections, autoimmune diseases, and cancer.

Product Information

Category Immune Checkpoint Cell Lines
Cell Line Name CHO-K1-KIR-Stable Cell Line
Protein Family Killer-cell immunoglobulin-like receptor family
Gene KIR
Species Hamster
Host Cell Line CHOK1
Cell Type Chinese hamster ovary cell line
Morphology Epithelial
Growth Properties Adherent
Recommended Medium F12K, 10% FBS, 8 μg/ml Puromycin
Freeze Medium 95% complete growth medium + 5% DMSO
Storage Method Frozen in liquid nitrogen.
Stability Validated for at least 10 passages
Mycoplasma Negative
Sterility Testing Negative
Shipping Shipping in dry ice
Biosafety Level BSL-1
Caution For Research Use Only
For research use only. Not for any other purpose.
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