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CHO-K1-M1-Stable Cell Line

Catalog Number CBCL-0053
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Unit Quantity 1 x 10^6 cells / 1.0 ml

Introduction

Recombinant CHO-K1 cells have been engineered to stably overexpress human cholinergic receptor muscarinic 1 (M1) on their surface. These cells contain high levels of the G protein Gαq, which is essential for coupling with the receptor in downstream signaling pathways.

Application

Drug screening and biological assays

Background

This gene encodes a muscarinic acetylcholine receptor, which is a G protein-coupled receptor that mediates various cellular responses, including the regulation of heart rate, smooth muscle contraction, and glandular secretion.

Product Information

Category GPCR Cell Lines
Cell Line Name CHO-K1-M1-Stable Cell Line
Protein Family Acetylcholine receptor (muscarinic)
Gene M1/CHRM1
NCBI Gene ID 1128
Species Hamster
Host Cell Line CHOK1
Cell Type Chinese hamster ovary cell line
Morphology Epithelial
Growth Properties Adherent
Storage Method Frozen in liquid nitrogen.
Stability Validated for at least 10 passages
Mycoplasma Negative
Sterility Testing Negative
Shipping Shipping in dry ice
Caution For Research Use Only
For research use only. Not for any other purpose.