CHO-K1-M2/Gα15-Stable Cell Line

Introduction

Recombinant CHO-K1 cells have been created to stably overexpress human cholinergic receptor muscarinic 2 (M2) on their surface. These cells contain high levels of the G protein Gαi, which is crucial for coupling with the receptor in downstream signaling pathways.

Application

Drug screening and biological assays

Background

This gene encodes a muscarinic acetylcholine receptor, which is a G protein-coupled receptor that plays a role in regulating cardiac function, smooth muscle contraction, and neurotransmitter release in the central nervous system.

Product Information