CHO-K1-mouse TIGIT-Stable Cell Line
| Catalog Number | CBCL-0534 |
| Price | Online Inquiry |
| Unit Quantity | 1 x 10^6 cells / 1.0 ml |
Introduction
The CHO-K1-mouse TIGIT-Stable Cell Line consists of recombinant CHO-K1 cells that stably overexpress mouse T cell immunoreceptor with Ig and ITIM domains (TIGIT) on their surface.
Application
Drug screening and biological assays
Background
TIGIT (T cell immunoreceptor with Ig and ITIM domains) is an inhibitory receptor expressed on T cells and NK cells. It competes with CD226 for binding to CD155/PVR on target cells, delivering an inhibitory signal that suppresses immune cell activation. TIGIT is upregulated in tumor-infiltrating lymphocytes and contributes to immune evasion in cancer.
Product Information
| Category | Immune Checkpoint Cell Lines |
| Cell Line Name | CHO-K1-mouse TIGIT-Stable Cell Line |
| Protein Family | T cell immunoreceptor with Ig and ITIM domains family |
| Gene | TIGIT |
| Species | Hamster |
| Host Cell Line | CHOK1 |
| Cell Type | Chinese hamster ovary cell line |
| Morphology | Epithelial |
| Growth Properties | Adherent |
| Recommended Medium | F12, 10% FBS, 8μg/ml Puromycin |
| Freeze Medium | 95% complete growth medium + 5% DMSO |
| Storage Method | Frozen in liquid nitrogen. |
| Stability | Validated for at least 10 passages |
| Mycoplasma | Negative |
| Sterility Testing | Negative |
| Shipping | Shipping in dry ice |
| Biosafety Level | BSL-1 |
| Caution | For Research Use Only |
For research use only. Not for any other purpose.