CHO-K1-MT2/Gα15-Stable Cell Line
| Catalog Number | CBCL-0127 |
| Price | Online Inquiry |
| Unit Quantity | 1 x 10^6 cells / 1.0 ml |
Introduction
Recombinant CHO-K1 cells have been developed to stably overexpress human melatonin receptor 1B (MT2) on their surface. These cells contain high levels of the G protein Gαi, which is crucial for coupling with the receptor in downstream signaling pathways.
Application
Drug screening and biological assays
Background
Melatonin receptor 1B (MTNR1B), also known as MT2, is a G protein-coupled receptor that binds melatonin and is involved in the regulation of circadian rhythms, sleep, and metabolism.
Product Information
| Category | GPCR Cell Lines |
| Cell Line Name | CHO-K1-MT2/Gα15-Stable Cell Line |
| Protein Family | Melatonin receptor |
| Gene | MT2/MTNR1B |
| NCBI Gene ID | 4544 |
| Species | Hamster |
| Host Cell Line | CHOK1 |
| Cell Type | Chinese hamster ovary cell line |
| Morphology | Epithelial |
| Growth Properties | Adherent |
| Storage Method | Frozen in liquid nitrogen. |
| Stability | Validated for at least 10 passages |
| Mycoplasma | Negative |
| Sterility Testing | Negative |
| Shipping | Shipping in dry ice |
| Caution | For Research Use Only |
For research use only. Not for any other purpose.