CHO-K1-NIACR1/Gα15-Stable Cell Line
| Catalog Number | CBCL-0114 |
| Price | Online Inquiry |
| Unit Quantity | 1 x 10^6 cells / 1.0 ml |
Introduction
Recombinant CHO-K1 cells have been designed to stably overexpress the human nicotinic acid receptor (NIACR1), also known as the hydroxycarboxylic acid receptor 2 (HCAR2), on their surface, and they contain high levels of the G protein Gαi, which is involved in coupling with the receptor to facilitate downstream signaling pathways.
Application
Drug screening and biological assays
Background
G protein-coupled receptor 109A (GPR109A), also known as niacin receptor 1 (NIACR1), is a receptor for niacin (vitamin B3) and is involved in the regulation of lipid metabolism and anti-inflammatory responses.
Product Information
| Category | GPCR Cell Lines |
| Cell Line Name | CHO-K1-NIACR1/Gα15-Stable Cell Line |
| Protein Family | Hydroxycarboxylic acid receptor |
| Gene | GPR109A/NIACR1 |
| Species | Hamster |
| Host Cell Line | CHOK1 |
| Cell Type | Chinese hamster ovary cell line |
| Morphology | Epithelial |
| Growth Properties | Adherent |
| Storage Method | Frozen in liquid nitrogen. |
| Stability | Validated for at least 10 passages |
| Mycoplasma | Negative |
| Sterility Testing | Negative |
| Shipping | Shipping in dry ice |
| Caution | For Research Use Only |
For research use only. Not for any other purpose.